Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.61 |
| ▸ | HTR6 | P50406 | 12/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.51 |
| ▸ | HTR3B | O95264 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925235 | 0.88 | ADRB1 (0.61) | ADRB1HTR6HTR3EHTR3BHTR3A | |
| SCHEMBL18838611 | 0.86 | ADRB1 (0.46) | ADRB1HTR6HTR3EHTR3BHTR3A | |
| SCHEMBL4422034 | 0.82 | HTR6 (0.49) | ADRB1HTR6HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL4573413 | 0.81 | HTR6 (0.50) | ADRB1HTR6KDM4EALDH1A1LMNA | |
| SCHEMBL2984679 | 0.77 | ADRB1 (0.73) | ADRB1HTR6HTR3EHTR3BHTR3A | |
| SCHEMBL232689 | 0.77 | ADRB1 (1.00) | ADRB1HTR6HTR3EHTR3BHTR3A | |
| SCHEMBL2929064 | 0.77 | HTR6 (0.53) | ADRB1HTR6HTR3EHTR3BHTR3A | |
| SCHEMBL1748256 | 0.75 | HTR6 (0.54) | ADRB1HTR6HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL2959681 | 0.75 | ADRB1 (0.96) | ADRB1HTR6HTR3EHTR3BHTR3A | |
| Piperazine SCHEMBL28293494 | 0.75 | ADRB1 (0.96) | ADRB1HTR6HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |