Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.39 |
| ▸ | CES1 | P23141 | 5/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29470949 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15CES2CES1KEAP1 | |
| SCHEMBL24710385 | 0.95 | ALDH1A1 (0.54) | ALDH1A1ALOX15CES2CES1KEAP1 | |
| SCHEMBL28525271 | 0.89 | ALDH1A1 (0.54) | ALDH1A1ALOX15CES2CES1KEAP1 | |
| SCHEMBL28829562 | 0.85 | CES2 (0.48) | ALDH1A1ALOX15CES2CES1KEAP1 | |
| SCHEMBL7728912 | 0.84 | CES2 (0.53) | ALDH1A1ALOX15CES2CES1CYP11B1 | |
| SCHEMBL9793665 | 0.83 | ALDH1A1 (0.45) | ALDH1A1ALOX15CES2CES1KEAP1 | |
| SCHEMBL30180915 | 0.83 | ALDH1A1 (0.45) | ALDH1A1ALOX15CES2CES1KEAP1 | |
| SCHEMBL367845 | 0.81 | ALDH1A1 (0.43) | ALDH1A1ALOX15CES2CES1KEAP1 | |
| SCHEMBL591163 | 0.81 | ALDH1A1 (0.43) | ALDH1A1ALOX15CES2CES1KEAP1 | |
| SCHEMBL13250855 | 0.81 | ALDH1A1 (0.43) | ALDH1A1ALOX15CES2CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486706-B | Synthesis method of 2,4, 5-trifluoro phenylacetic acid | 山东国邦药业有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117486706-A | Synthesis method of 2,4, 5-trifluoro phenylacetic acid | 山东国邦药业有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-112142595-A | Preparation method and purification method of ethyl 2, 4, 5-trifluorobenzoylacetate | 江苏恒盛药业有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-107376875-A | A kind of preparation and application of the beta cyclodextrin porous material with quick adsorption ability | 湖南理工学院 | 2017-11-24 | — | — | CN | claimed |
| CN-103553900-B | Synthesis method of 2,4,5-trifluorophenylacetic acid | ZHEJIANG ZHONGXIN CHEMICALS CO LTD | 2015-05-20 | — | — | CN | claimed |
| CN-103553900-A | Synthesis method of 2,4,5-trifluorophenylacetic acid | ZHEJIANG ZHONGXIN CHEMICALS CO LTD | 2014-02-05 | — | — | CN | claimed |
| US-4948894-A | BACTERICIDE INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1990-08-14 | — | — | US | claimed |
| EP-0164619-B1 | 2,4,5-TRIHALO OR 2,3,4,5-TETRAHALO BENZENE DERIVATIVES AND PROCESS FOR PRODUCING THEM | BAYER AG (DE) | 1988-10-12 | — | — | EP | claimed |
| JP-59098038-A | — | — | None | — | — | JP | disclosed |
| EP-4073062-B1 | FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | RYVU THERAPEUTICS S A (PL) | 2026-04-29 | — | — | EP | disclosed |
| EP-4157831-B1 | PROCESSES OF PREPARING A JAK1 INHIBITOR | INCYTE CORP (US) | 2024-10-30 | — | — | EP | disclosed |
| CN-117486706-B | Synthesis method of 2,4, 5-trifluoro phenylacetic acid | 山东国邦药业有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-20240091733-A1 | SYSTEM OF MODULAR KITS TO PRODUCE CHEMICAL TARGETS OF INTEREST | ODH IP Corp. (US) | 2024-03-21 | — | — | US | disclosed |
| CN-114605223-B | Method for preparing 2,4, 5-trifluoro-benzyl bromide by using 2,4, 5-trifluoro-benzyl chloride | 浙江永太科技股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-0191185-A1 | Quinoline-carboxylic acid derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |
| EP-0176846-A2 | 3-Amino-2-benzoyl-acrylic-acid derivatives and process for their preparation | BAYER AG (DE) | 1986-04-09 | — | — | EP | disclosed |
| EP-0168737-A2 | Process for the preparation of halogenated quinolinoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |
| EP-0168732-A2 | Process for the preparation of halogenated aroylacetic acid esters | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |
| EP-0155587-A1 | 1,7-Diamino-1,4-dihydro-4-oxo-3(aza)quinoline-carboxylic acids, process for their preparation and their use in treating bacterial diseases | BAYER AG (DE) | 1985-09-25 | — | — | EP | disclosed |
| JP-S5998038-A | 2,4,5-TRIFLUOROBENZOIC ACID PHENYL ESTER | CHISSO CORP | 1984-06-06 | — | — | JP | disclosed |