Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089410 | 1.00 | MEN1 (0.34) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL8295150 | 0.83 | — | — | |
| SCHEMBL8054410 | 0.81 | — | — | |
| SCHEMBL8036824 | 0.81 | — | — | |
| SCHEMBL13272872 | 0.78 | MMP1 (0.32) | MMP1MMP2MMP8MMP13 | |
| SCHEMBL14613751 | 0.76 | MMP1 (0.36) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL8279593 | 0.75 | MEN1 (0.32) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL15491270 | 0.74 | MMP1 (0.35) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL8271464 | 0.74 | MMP1 (0.33) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL12040047 | 0.72 | MEN1 (0.33) | MEN1KMT2AMMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070358-A2 | N-CYCLOPROPYL-HYDROXYPROLINE-BASED TRIPEPTIDIC HEPATITIS C SERINE PROTEASE INHIBITORS CONTAINING AN ISOINDOLE, PYRROLOPYRIDINE, PYRROLOPYRIMIDINE OR PYRROLOPYRAZINE HETEROCYCLE IN THE SIDE CHAIN | PHENOMIX CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |