Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | PER2 | O15055 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.30 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089410 | 0.75 | MEN1 (0.34) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL4574002 | 0.75 | MEN1 (0.34) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL15491270 | 0.71 | MMP1 (0.35) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL8280382 | 0.71 | PER2 (0.33) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL12040114 | 0.69 | MEN1 (0.33) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL12040047 | 0.69 | MEN1 (0.33) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL13759912 | 0.68 | MEN1 (0.32) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL8278785 | 0.68 | MMP1 (0.33) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL8271464 | 0.67 | MMP1 (0.33) | MEN1KMT2AMMP1MMP2MMP8 | |
| SCHEMBL6755694 | 0.66 | MMP1 (0.43) | MEN1KMT2AMMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005113581-A1 | SUBSTITUTED PROLINES AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005021584-A2 | NOVEL PEPTIDOMIMETIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-03-10 | — | — | WO | disclosed |