SCHEMBL4574080

SCHEMBL4574080

O=C(NC1CC1O)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 2/20 0.60
ALDH1A1 P00352 3/20 0.58
GAA P10253 1/20 0.58
TSHR P16473 1/20 0.56
EPHX1 P07099 1/20 0.52
KDM1A O60341 1/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CTSL P07711 1/20 0.50
CTSB P07858 1/20 0.50
CTSK P43235 1/20 0.50
TLR4 O00206 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13370746 0.95 CPB1 (0.59) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL4088176 0.95 CPB1 (0.59) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL4093654 0.95 CPB1 (0.59) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL4088179 0.95 CPB1 (0.59) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL13974659 0.91 ALDH1A1 (0.60) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL10188414 0.89 CPB1 (0.56) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL2621447 0.89 CPB1 (0.56) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL16800373 0.89 CPB1 (0.56) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL24324120 0.88 CPB1 (0.61) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL6803264 0.87 CPB1 (0.54) CPB1ALDH1A1GAATSHREPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008095912-A2 ENANTIOPURE PHARMACOLOGICALLY ACTIVE TRICYCLIC BENZIMIDAZOLES NYCOMED GMBH (DE) 2008-08-14 WO disclosed