Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24415092 | 0.86 | ALDH1A1 (0.50) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL8768934 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TDP1 | |
| SCHEMBL6247510 | 0.77 | — | — | |
| SCHEMBL4800733 | 0.77 | — | — | |
| SCHEMBL22435396 | 0.76 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL22918815 | 0.73 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL13389759 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL16300102 | 0.73 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL982870 | 0.72 | TSHR (0.32) | TDP1 | |
| Trimethylammonium SCHEMBL2420334 | 0.72 | ALDH1A1 (0.83) | ALDH1A1POLBMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2559484-A1 | Coordination complex system comprising a second bulding block without donor moiety | Universiteit van Amsterdam (NL) | 2013-02-20 | — | — | EP | disclosed |
| WO-2008075148-A2 | TRICYCLIC INHIBITORS OF CARBONIC ANHYDRASE | PFIZER PRODUCTS INC. (US) | 2008-06-26 | — | — | WO | disclosed |