SCHEMBL982870

SCHEMBL982870

C=C(C(=O)O)N(C)C(C)=O

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
THPO P40225 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8769303 0.74 TSHR (0.33) TSHRTHPOFFAR3LCKFYN
SCHEMBL14541725 0.73
SCHEMBL1015918 0.73
SCHEMBL4574336 0.72 ALDH1A1 (0.50) TDP1
SCHEMBL992383 0.71
SCHEMBL4302318 0.69
Methacrylic Acid SCHEMBL284735 0.69 TDP1 (0.44) TSHRTHPOFFAR3LCKFYN
Methacrylic Acid SCHEMBL28229822 0.69 TDP1 (0.44) TSHRTHPOFFAR3LCKFYN
SCHEMBL4199077 0.69 TDP1 (0.38) TDP1
Chloromethane SCHEMBL8972580 0.69 ALDH1A1 (0.40) TSHRTHPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108132569-B Mirror unit and display device including the same 乐金显示有限公司 2020-12-15 CN disclosed
US-8283276-B2 Coordination complex system comprising tautomeric ligands UNIVERSITEIT VAN AMSTERDAM (NL) 2012-10-09 US disclosed
EP-2220099-B1 COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS UNIV AMSTERDAM (NL) 2012-06-27 EP disclosed
US-8058429-B2 Diazaphosphacycle transition metal complexes WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-11-15 US disclosed
US-20110003959-A1 COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS UNIVERSITEIT VAN AMSTERDAM 2011-01-06 US disclosed
US-20100222583-A1 DIAZAPHOSPHACYCLE TRANSITION METAL COMPLEXES WISCONSIN ALUMNI RESEARCH FOUNDATION 2010-09-02 US disclosed
EP-2220099-A1 COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS Universiteit van Amsterdam (NL) 2010-08-25 EP disclosed
US-7737272-B2 Diazaphosphacycle transition metal complexes WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-06-15 US disclosed
WO-2009065856-A1 COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS UNIVERSITEIT VAN AMSTERDAM (NL) 2009-05-28 WO disclosed
US-7507820-B2 Diazaphosphacycles WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-03-24 US disclosed
US-7071357-B2 Diazaphosphacycles WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-07-04 US disclosed
US-20050202507-A1 Diazaphosphacycles WISCONSIN ALUMNI RESEARCH FOUNDATION 2005-09-15 US disclosed
WO-2005042546-A2 DIAZAPHOSPHACYCLES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2005-05-12 WO disclosed
US-20040176322-A1 Diazaphosphacycle transition metal complexes WISCONSIN ALUMNI RESEARCH FOUNDATION 2004-09-09 US disclosed
US-20040171856-A1 Synthesis of diazaphosphacycles WISCONSIN ALUMNI RESEARCH FOUNDATION 2004-09-02 US disclosed
EP-1409495-A1 DIAZAPHOSPHACYCLES Wisconsin Alumini Research Foundation (US) 2004-04-21 EP disclosed
US-20030055254-A1 Diazaphosphacycles UNITED STATES DEPARTMENT OF ENERGY 2003-03-20 US disclosed
WO-2003010174-A1 DIAZAPHOSPHACYCLES WISCONSIN ALUMINI RESEARCH FOUNDATION (US) 2003-02-06 WO disclosed
US-5827794-A SULFONATED 2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-10-27 US disclosed
US-5756838-A Method of asymmetrically synthesizing optically active compounds using supported phase chiral sulfonated BINAP catalyst CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100222583-A1 DIAZAPHOSPHACYCLE TRANSITION METAL COMPLEXES MCM3, MT-ND3, IDH3A TSHR 4353/4885THPO 1420/4885FFAR3 4565/4885
US-20050202507-A1 Diazaphosphacycles CDK14, CDK15, H1-4 TSHR 2445/4885THPO 1554/4885FFAR3 4632/4885
US-20110003959-A1 COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS XRN2, LIG1, H1-2 TSHR 2644/4885THPO 3861/4885FFAR3 4361/4885
US-20030055254-A1 Diazaphosphacycles IDH2, PHOSPHO1, PDPK1 TSHR 496/4885THPO 2650/4885FFAR3 237/4885
US-20040171856-A1 Synthesis of diazaphosphacycles PFKFB1, IDH2, PFKFB2 TSHR 663/4885THPO 2991/4885FFAR3 384/4885
US-20040176322-A1 Diazaphosphacycle transition metal complexes MCM3, MT-ND3, IDH3A TSHR 4341/4885THPO 1599/4885FFAR3 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.