Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73654 | 0.88 | PDE4D (0.41) | PDE4DPDE4BPDE4APDE4CNPC1 | |
| SCHEMBL72181 | 0.87 | MGAM (0.43) | PDE4DPDE4BPDE4APDE4CNPC1 | |
| SCHEMBL73109 | 0.82 | MAOB (0.40) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL73967 | 0.78 | PDE4B (0.42) | PDE4DPDE4BPDE4APDE4CNPC1 | |
| SCHEMBL73651 | 0.76 | PDE4A (0.41) | PDE4DPDE4BPDE4APDE4CNPC1 | |
| SCHEMBL5018032 | 0.75 | PDE4B (0.46) | PDE4DPDE4BPDE4APDE4CNPC1 | |
| SCHEMBL4574940 | 0.74 | NPC1 (0.36) | PDE4DPDE4BPDE4APDE4CNPC1 | |
| SCHEMBL73553 | 0.73 | PDE4B (0.48) | PDE4DPDE4BPDE4APDE4CNPC1 | |
| SCHEMBL4574332 | 0.72 | PDE4B (0.41) | PDE4DPDE4BPDE4APDE4CNPC1 | |
| SCHEMBL3868904 | 0.72 | PDE4B (0.37) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081282-A2 | PROCESS FOR THE SYNTHESIS OF N9-(3,5-DICHLORO-4-PYRIDYL)-6- DIFLUOROMETHOXYBENZO(4,5)FURO(3,2-C)PYRIDINE-9-CARBOXAMIDE AND SALTS THEREOF | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-07-10 | — | — | WO | disclosed |