Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74507 | 0.82 | ALDH1A1 (0.47) | NPC1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL73469 | 0.77 | PDE4A (0.41) | PDE4DPDE4APDE4BPDE4CKMT2A | |
| SCHEMBL73967 | 0.77 | PDE4B (0.42) | NPC1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5506611 | 0.77 | PDE4A (0.40) | NPC1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11335559 | 0.77 | CYP1A2 (0.46) | NPC1CYP1A2KDM4ERAB9AALDH1A1 | |
| SCHEMBL5018032 | 0.76 | PDE4B (0.46) | NPC1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL15016077 | 0.75 | PDE4D (0.34) | NPC1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4574337 | 0.74 | PDE4D (0.38) | NPC1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5973105 | 0.74 | ALDH1A1 (0.38) | NPC1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL15016128 | 0.74 | PDE4A (0.33) | PDE4DPDE4APDE4BPDE4CCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081282-A2 | PROCESS FOR THE SYNTHESIS OF N9-(3,5-DICHLORO-4-PYRIDYL)-6- DIFLUOROMETHOXYBENZO(4,5)FURO(3,2-C)PYRIDINE-9-CARBOXAMIDE AND SALTS THEREOF | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-07-10 | — | — | WO | disclosed |