Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 9/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2022959 | 0.84 | XIAP (0.40) | GRM2MLNR | |
| SCHEMBL4590377 | 0.81 | MLNR (0.42) | GRM2RIPK1TACR1KDM4ESMN1; SMN2 | |
| SCHEMBL4573863 | 0.78 | SCN9A (0.36) | GRM2RIPK1TACR1KDM4ESMN1; SMN2 | |
| SCHEMBL14013388 | 0.78 | SCN9A (0.36) | GRM2RIPK1TACR1KDM4ESMN1; SMN2 | |
| SCHEMBL14013327 | 0.78 | MLNR (0.36) | RIPK1TACR1KDM4ESMN1; SMN2MLNR | |
| SCHEMBL4574465 | 0.76 | GRIN2D (0.48) | RIPK1 | |
| SCHEMBL14013955 | 0.75 | GRIN2D (0.37) | GRM2RIPK1MLNR | |
| SCHEMBL14013795 | 0.75 | MLNR (0.38) | RIPK1MLNR | |
| SCHEMBL4573901 | 0.75 | RIPK1 (0.36) | GRM2RIPK1MLNR | |
| SCHEMBL14013797 | 0.75 | RIPK1 (0.43) | RIPK1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |