Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963151 | 0.80 | HPGD (0.44) | HPGDTSHRALDH1A1RAB9A | |
| SCHEMBL21148184 | 0.80 | HPGD (0.46) | LMNANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL24016888 | 0.79 | HPGD (0.55) | LMNANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL17327862 | 0.77 | KMT2A (0.41) | LMNANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL4735120 | 0.75 | HTT (0.56) | LMNANPC1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL4574011 | 0.74 | SMN1; SMN2 (0.50) | LMNANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL16078374 | 0.72 | FLT1 (0.44) | NPC1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL7191112 | 0.70 | HPGD (0.46) | NPC1HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL5771336 | 0.70 | HPGD (0.44) | LMNANPC1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL4574791 | 0.70 | MEN1 (0.45) | NPC1HPGDKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095912-A2 | ENANTIOPURE PHARMACOLOGICALLY ACTIVE TRICYCLIC BENZIMIDAZOLES | NYCOMED GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |