Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1943292 | 0.83 | RAB9A (0.51) | MEN1KMT2AALDH1A1NPC1HPGD | |
| SCHEMBL4963151 | 0.80 | HPGD (0.44) | ALDH1A1HPGDRAB9A | |
| SCHEMBL5776033 | 0.79 | CES2 (0.46) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4965838 | 0.75 | KMT2A (0.47) | MEN1KMT2AALDH1A1NPC1HPGD | |
| SCHEMBL18544668 | 0.74 | LMNA (0.50) | MEN1KMT2AALDH1A1NPC1HPGD | |
| SCHEMBL5771336 | 0.74 | HPGD (0.44) | MEN1KMT2ANPC1HPGDUSP2 | |
| SCHEMBL1942112 | 0.71 | ALOX5 (0.51) | MEN1KMT2AALDH1A1NPC1HPGD | |
| SCHEMBL4574595 | 0.70 | LMNA (0.46) | MEN1KMT2AALDH1A1NPC1HPGD | |
| SCHEMBL5773245 | 0.69 | SMN1; SMN2 (0.58) | ALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL4962542 | 0.68 | HPGD (0.50) | MEN1KMT2AALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095912-A2 | ENANTIOPURE PHARMACOLOGICALLY ACTIVE TRICYCLIC BENZIMIDAZOLES | NYCOMED GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |