Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039743 | 0.81 | GRIN2B (0.50) | CARM1PRMT6 | |
| SCHEMBL64031 | 0.79 | CARM1 (0.63) | CARM1PRMT6MAPTALOX12CHRM2 | |
| SCHEMBL4586847 | 0.79 | CARM1 (0.56) | CARM1PRMT6MAPTALOX12CHRM2 | |
| SCHEMBL4495643 | 0.79 | RXFP1 (0.48) | CARM1PRMT6MAPTALOX12RXFP1 | |
| SCHEMBL4495638 | 0.79 | RXFP1 (0.48) | CARM1PRMT6MAPTALOX12RXFP1 | |
| Hydrochloric Acid SCHEMBL21879607 | 0.78 | CARM1 (0.62) | CARM1PRMT6MAPTALOX12CHRM2 | |
| SCHEMBL9667976 | 0.76 | POLB (0.62) | CARM1PRMT6MAPTALOX12CHRM2 | |
| SCHEMBL20557084 | 0.73 | KDM1A (0.50) | CHRM2TACR1SLC6A4 | |
| SCHEMBL21094339 | 0.73 | KDM1A (0.50) | CHRM2TACR1SLC6A4 | |
| SCHEMBL20557083 | 0.73 | KDM1A (0.50) | CHRM2TACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |