Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802110 | 0.85 | LMNA (0.68) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11867695 | 0.83 | SMN1; SMN2 (0.50) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL24791584 | 0.81 | MEN1 (0.53) | LMNAHTTSMN1; SMN2NPC1TDP1 | |
| SCHEMBL24791588 | 0.79 | TDP1 (0.47) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4069104 | 0.79 | LMNA (0.70) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1494554 | 0.79 | TDP1 (0.55) | LMNAHTTSMN1; SMN2TDP1MEN1 | |
| SCHEMBL19389695 | 0.79 | TDP1 (0.55) | LMNAHTTSMN1; SMN2TDP1MEN1 | |
| SCHEMBL13756091 | 0.77 | GLA (0.63) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5023540 | 0.76 | HTT (0.73) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23057256 | 0.76 | LMNA (0.73) | LMNAHTTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307570-A | Cyclopropyl borate compound and preparation method thereof | 南方科技大学 | 2024-07-09 | — | — | CN | disclosed |
| US-9763978-B2 | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable covalent bonds and their use in treating celiac disease | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2017-09-19 | — | — | US | disclosed |
| CN-101360505-B | Pharmaceutical composition comprising a polymeric binder comprising a non-hydrolysable covalent bond and its use in the treatment of celiac disease | UNIVERSITE DE MONTREAL (CA) | 2015-09-09 | — | — | CN | disclosed |
| US-20150064131-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE | VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) | 2015-03-05 | — | — | US | disclosed |
| CN-102784165-B | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable covalent bonds and their use in treating celiac disease | VALORISATION RECH LTD PARTNERS | 2015-02-25 | — | — | CN | disclosed |
| US-8883133-B2 | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable their use in treating celiac disease | VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) | 2014-11-11 | — | — | US | disclosed |
| US-8784792-B2 | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable covalent bonds and their use in treating celiac disease | Valorization-Recherche Limited Partnership (CA) | 2014-07-22 | — | — | US | disclosed |
| CN-102784165-A | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable covalent bonds and their use in treating celiac disease | VALORISATION RECH LTD PARTNERS | 2012-11-21 | — | — | CN | disclosed |
| US-20120244105-A1 | Pharmaceutical Compositions Comprising Polymeric Binders with Non-Hydrolysable Covalent Bonds and Their Use in Treating Celiac Disease | VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) | 2012-09-27 | — | — | US | disclosed |
| CN-101360505-A | Pharmaceutical composition comprising a polymeric binder comprising a non-hydrolysable covalent bond and its use in the treatment of celiac disease | VALORISATION RECH LTD PARTNERS (CA) | 2009-02-04 | — | — | CN | disclosed |
| US-20080254099-A1 | Such as high molecular weight copolymer of hydroxyethyl methacrylate and 4-styrene sulfonic acid sodium salt; decreasing interaction of gluten or peptide degradation products with intestinal tract; breads | VALORISATION-RECHERCHE, LIMITED (CA) | 2008-10-16 | — | — | US | disclosed |
| EP-1948201-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE | UNIVERSITE DE MONTREAL (CA) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007053935-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE | UNIVERSITE DE MONTREAL (CA) | 2007-05-18 | — | — | WO | disclosed |