Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14079063 | 1.00 | HCRTR1 (0.53) | HCRTR1HCRTR2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4575140 | 0.85 | FKBP1A (0.55) | ALDH1A1CYP2C9CYP2C19FKBP1AACE | |
| SCHEMBL14079069 | 0.85 | FKBP1A (0.55) | ALDH1A1CYP2C9CYP2C19FKBP1AACE | |
| SCHEMBL4575683 | 0.84 | FKBP1A (0.54) | ALDH1A1CYP2C9FKBP1AMAPK1 | |
| SCHEMBL14079076 | 0.84 | FKBP1A (0.54) | ALDH1A1CYP2C9FKBP1AMAPK1 | |
| SCHEMBL14079073 | 0.83 | FKBP1A (0.60) | FKBP1A | |
| SCHEMBL4575722 | 0.83 | FKBP1A (0.60) | FKBP1A | |
| SCHEMBL13865067 | 0.80 | HCRTR1 (0.62) | HCRTR1HCRTR2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4575519 | 0.78 | POLB (0.44) | ALDH1A1CYP2C9FKBP1AMAPK1 | |
| SCHEMBL14079060 | 0.78 | POLB (0.44) | ALDH1A1CYP2C9FKBP1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | JERINI AG (DE) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | CCNB1, CCNB2, CCNA1 | HCRTR1 2199/4885HCRTR2 2740/4885ALDH1A1 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.