Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14079076 | 1.00 | FKBP1A (0.54) | FKBP1APOLBATMMEN1KMT2A | |
| SCHEMBL4575722 | 0.94 | FKBP1A (0.60) | FKBP1APOLB | |
| SCHEMBL14079073 | 0.94 | FKBP1A (0.60) | FKBP1APOLB | |
| SCHEMBL14079069 | 0.91 | FKBP1A (0.55) | FKBP1APOLBCYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL4575140 | 0.91 | FKBP1A (0.55) | FKBP1APOLBCYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL14079060 | 0.89 | POLB (0.44) | FKBP1APOLBATMMEN1KMT2A | |
| SCHEMBL4575519 | 0.89 | POLB (0.44) | FKBP1APOLBATMMEN1KMT2A | |
| SCHEMBL4575372 | 0.84 | HCRTR1 (0.53) | FKBP1ACYP2C9ALDH1A1MAPK1 | |
| SCHEMBL14079063 | 0.84 | HCRTR1 (0.53) | FKBP1ACYP2C9ALDH1A1MAPK1 | |
| SCHEMBL8102664 | 0.79 | FKBP1A (0.64) | FKBP1APOLBATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | JERINI AG (DE) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194524-A1 | Compounds For the Inhibition of Undesired Cell Proliferation and Use Thereof | CCNB1, CCNB2, CCNA1 | FKBP1A 1404/4885POLB 449/4885ATM 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.