Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.64 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.64 |
| ▸ | GSK3A | P49840 | 1/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.58 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.58 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585150 | 0.86 | HTT (0.61) | KMT2AMEN1SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL23355638 | 0.84 | NPC1 (0.60) | KMT2AMEN1SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL4908980 | 0.84 | KMT2A (0.82) | KMT2AMEN1SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL6490488 | 0.81 | KMT2A (0.74) | KMT2AMEN1SLC6A2SLC6A3SMN1; SMN2 | |
| Difenpiramide SCHEMBL29238669 | 0.81 | KMT2A (1.00) | KMT2AMEN1SLC6A2SLC6A3SMN1; SMN2 | |
| Difenpiramide SCHEMBL23833 | 0.81 | KMT2A (1.00) | KMT2AMEN1SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL29270879 | 0.81 | KMT2A (1.00) | KMT2AMEN1SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL31240699 | 0.80 | MAPK10 (0.75) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK10 | |
| SCHEMBL29083803 | 0.80 | MAPK10 (0.75) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK10 | |
| SCHEMBL16607690 | 0.80 | F2 (0.85) | KMT2AMEN1SMN1; SMN2ALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| US-20050137212-A1 | Hppars activators | SMITHKLINE BEECHAM CORPORATION | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137212-A1 | Hppars activators | PPARG, PPARA, PPARD | KMT2A 4023/4885MEN1 4576/4885SLC6A2 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.