Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601233 | 0.80 | LMNA (0.46) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL509325 | 0.80 | LMNA (0.46) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL11673321 | 0.78 | ALDH1A1 (0.38) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL3727526 | 0.78 | TSHR (0.36) | KMT2ATSHRITGB2ICAM1ITGAL | |
| SCHEMBL2036505 | 0.78 | TSHR (0.41) | ALDH1A1TSHR | |
| SCHEMBL31391242 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL1794189 | 0.73 | ALDH1A1 (0.36) | ALDH1A1LMNA | |
| SCHEMBL6157162 | 0.73 | LMNA (0.43) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL21295981 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8733878 | 0.72 | KMT2A (0.32) | ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763978-B2 | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable covalent bonds and their use in treating celiac disease | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2017-09-19 | — | — | US | disclosed |
| US-20150064131-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE | VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) | 2015-03-05 | — | — | US | disclosed |
| US-8883133-B2 | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable their use in treating celiac disease | VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) | 2014-11-11 | — | — | US | disclosed |
| US-8784792-B2 | Pharmaceutical compositions comprising polymeric binders with non-hydrolysable covalent bonds and their use in treating celiac disease | Valorization-Recherche Limited Partnership (CA) | 2014-07-22 | — | — | US | disclosed |
| US-20120244105-A1 | Pharmaceutical Compositions Comprising Polymeric Binders with Non-Hydrolysable Covalent Bonds and Their Use in Treating Celiac Disease | VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) | 2012-09-27 | — | — | US | disclosed |
| US-20080254099-A1 | Such as high molecular weight copolymer of hydroxyethyl methacrylate and 4-styrene sulfonic acid sodium salt; decreasing interaction of gluten or peptide degradation products with intestinal tract; breads | VALORISATION-RECHERCHE, LIMITED (CA) | 2008-10-16 | — | — | US | disclosed |
| EP-1948201-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE | UNIVERSITE DE MONTREAL (CA) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007053935-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE | UNIVERSITE DE MONTREAL (CA) | 2007-05-18 | — | — | WO | disclosed |
| US-5883102-A | Pharmaceutically active compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |
| EP-0858451-A1 | PHARMACEUTICALLY ACTIVE QUINAZOLINE COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997014686-A1 | PHARMACEUTICALLY ACTIVE QUINAZOLINE COMPOUNDS | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-04-24 | — | — | WO | disclosed |