SCHEMBL4576256

SCHEMBL4576256

CC1=C([Zr])CC=C1.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
KCNH2 Q12809 2/20 0.36
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TAAR1 Q96RJ0 4/20 0.35
ATM Q13315 1/20 0.35
GSK3A P49840 1/20 0.35
GSK3B P49841 1/20 0.35
MGLL Q99685 1/20 0.35
DAO P14920 1/20 0.35
PKM P14618 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
CYP2A6 P11509 1/20 0.34
HTR2A P28223 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL9066873 0.82 ALDH1A1 (0.38) ALDH1A1HSD17B10TAAR1ATMMGLL
SCHEMBL813727 0.79
SCHEMBL27463429 0.77
Iodide SCHEMBL29025924 0.77
Bromide SCHEMBL29025903 0.77
Hydrochloric Acid SCHEMBL27496985 0.77
SCHEMBL4868254 0.76 MAOB (0.35) MAOAMAOBKCNH2ALDH1A1HPGD
SCHEMBL7032648 0.76 MAOA (0.36) MAOAMAOBKCNH2ALDH1A1HPGD
Hydrochloric Acid SCHEMBL27492342 0.75
Bromide SCHEMBL28570339 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448568-A4 DICOPS CONTAINING ACETYLENIC SUBSTITUENTS EXXONMOBIL CHEM PATENTS INC (US) 2008-02-13 EP disclosed
EP-1448568-A2 DICOPS CONTAINING ACETYLENIC SUBSTITUENTS ExxonMobil Chemical Patents Inc. (US) 2004-08-25 EP disclosed
WO-2003040070-A2 DICOPS CONTAINING ACETYLENIC SUBSTITUENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-05-15 WO disclosed