Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 4/20 | 0.38 |
| ▸ | CCR8 | P51685 | 4/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenanthroline SCHEMBL28985719 | 0.82 | LMNA (0.64) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| Quinoline SCHEMBL2027950 | 0.80 | ALDH1A1 (0.65) | NUDT1AXLALDH1A1KDM4ELMNA | |
| Naphthalene SCHEMBL338595 | 0.80 | CYP2A6 (0.42) | NUDT1AXLALDH1A1HSP90AA1MAPT | |
| SCHEMBL28304525 | 0.79 | CCR1 (0.55) | NUDT1AXLALDH1A1KDM4ELMNA | |
| SCHEMBL29354893 | 0.79 | CCR1 (0.55) | NUDT1AXLALDH1A1KDM4ELMNA | |
| SCHEMBL8193 | 0.79 | CCR1 (0.55) | NUDT1AXLALDH1A1KDM4ELMNA | |
| Quinoline SCHEMBL27662086 | 0.79 | ALDH1A1 (0.63) | NUDT1AXLALDH1A1KDM4ELMNA | |
| Quinoline SCHEMBL28561469 | 0.79 | ALDH1A1 (0.63) | NUDT1AXLALDH1A1KDM4ELMNA | |
| SCHEMBL10630210 | 0.77 | CCR1 (0.52) | NUDT1AXLALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL3704753 | 0.77 | CCR1 (0.52) | NUDT1AXLALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300147-A1 | Detection and Treatment of Fibrotic Disorders | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2008-12-04 | — | — | US | claimed |
| WO-2005098041-A2 | DETECTION AND TREATMENT OF FIBROTIC DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-10-20 | — | — | WO | claimed |
| CN-102006777-A | Herbicidal coumpounds | SYNGENTA LTD | 2011-04-06 | — | — | CN | disclosed |
| US-20080300147-A1 | Detection and Treatment of Fibrotic Disorders | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2008-12-04 | — | — | US | disclosed |
| WO-2005098041-A2 | DETECTION AND TREATMENT OF FIBROTIC DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-10-20 | — | — | WO | disclosed |