SCHEMBL4576309

SCHEMBL4576309

C=Cc1ccc(C2=NCCO2)cc1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LSS P48449 1/20 0.42
ALDH1A1 P00352 2/20 0.41
KCNH2 Q12809 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
LTA4H P09960 1/20 0.40
MMP12 P39900 1/20 0.33
USP9X Q93008 1/20 0.33
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL27729578 0.93 ALDH1A1 (0.45) LSSALDH1A1KCNH2HRH3LTA4H
SCHEMBL132013 0.84 KCNH2 (0.49) LSSKCNH2HRH3LTA4HUSP9X
SCHEMBL2435102 0.81 LSS (0.45) LSSALDH1A1KCNH2HRH3LTA4H
SCHEMBL9181791 0.79 KCNH2 (0.43) LSSKCNH2HRH3LTA4HUSP9X
SCHEMBL23576315 0.77 KCNH2 (0.47) LSSALDH1A1KCNH2HRH3LTA4H
SCHEMBL9420292 0.77 KCNH2 (0.38) LSSKCNH2HRH3LTA4H
SCHEMBL14947206 0.77 LSS (0.40) LSSALDH1A1KCNH2HRH3LTA4H
SCHEMBL16771905 0.77 LSS (0.40) LSSALDH1A1KCNH2HRH3LTA4H
SCHEMBL10520360 0.76 KCNH2 (0.48) LSSKCNH2HRH3LTA4HMMP12
SCHEMBL9475161 0.76 KCNH2 (0.44) LSSKCNH2HRH3LTA4HUSP9X

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777358-A Oxazolinyl-containing copolymer, preparation method, application and composition 上海朗亿功能材料有限公司 2024-03-29 CN claimed
US-12247168-B2 Curable photochromic compositions including an oxazoline functional material TRANSITIONS OPTICAL, LTD. (IE) 2025-03-11 US disclosed
CN-117777358-A Oxazolinyl-containing copolymer, preparation method, application and composition 上海朗亿功能材料有限公司 2024-03-29 CN disclosed
US-20230059569-A1 Curable Photochromic Compositions Including an Oxazoline Functional Material TRANSITIONS OPTICAL, LTD. (IE) 2023-02-23 US disclosed
EP-4081595-A1 CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING AN OXAZOLINE FUNCTIONAL MATERIAL Transitions Optical, Ltd. (IE) 2022-11-02 EP disclosed
CN-114901748-A Curable photochromic compositions comprising oxazoline-functional materials 光学转变有限公司 2022-08-12 CN disclosed
WO-2021129940-A1 CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING AN OXAZOLINE FUNCTIONAL MATERIAL TRANSITIONS OPTICAL, LTD. (IE) 2021-07-01 WO disclosed
US-9763978-B2 Pharmaceutical compositions comprising polymeric binders with non-hydrolysable covalent bonds and their use in treating celiac disease VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) 2017-09-19 US disclosed
US-20150064131-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) 2015-03-05 US disclosed
US-8883133-B2 Pharmaceutical compositions comprising polymeric binders with non-hydrolysable their use in treating celiac disease VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) 2014-11-11 US disclosed
US-20120258247-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET NITTO DENKO CORPORATION (JP) 2012-10-11 US disclosed
US-20120244105-A1 Pharmaceutical Compositions Comprising Polymeric Binders with Non-Hydrolysable Covalent Bonds and Their Use in Treating Celiac Disease VALORISATION-RECHERCHE LIMITED PARTNERSHIP (CA) 2012-09-27 US disclosed
CN-102666768-A Adhesive composition and adhesive sheet NITTO DENKO CORP 2012-09-12 CN disclosed
US-20080254099-A1 Such as high molecular weight copolymer of hydroxyethyl methacrylate and 4-styrene sulfonic acid sodium salt; decreasing interaction of gluten or peptide degradation products with intestinal tract; breads VALORISATION-RECHERCHE, LIMITED (CA) 2008-10-16 US disclosed
EP-1948201-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE UNIVERSITE DE MONTREAL (CA) 2008-07-30 EP disclosed
WO-2007053935-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POLYMERIC BINDERS WITH NON-HYDROLYSABLE COVALENT BONDS AND THEIR USE IN TREATING CELIAC DISEASE UNIVERSITE DE MONTREAL (CA) 2007-05-18 WO disclosed
EP-0546570-B1 Vinyl alcohol copolymer having terminal amino group KURARAY CO (JP) 1997-04-16 EP disclosed
EP-0546570-A1 Vinyl alcohol copolymer having terminal amino group KURARAY CO., LTD. (JP) 1993-06-16 EP disclosed
EP-0523087-A1 HIGH IMPACT POLYETHYLENE TEREPHTHALATE-POLYCARBONATE BLEND COMPOSITIONS AlliedSignal Inc. (US) 1993-01-20 EP disclosed
WO-1991015545-A1 HIGH IMPACT POLYETHYLENE TEREPHTHALATE-POLYCARBONATE BLEND COMPOSITIONS ALLIED-SIGNAL INC. (US) 1991-10-17 WO disclosed