Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14140131 | 0.92 | SMN1; SMN2 (0.42) | SMN1; SMN2DHFRMEN1SLC22A1ALDH1A1 | |
| SCHEMBL30932949 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2DHFRMEN1SLC22A1ALDH1A1 | |
| SCHEMBL3258035 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2DHFRMEN1SLC22A1ALDH1A1 | |
| SCHEMBL4576056 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2DHFRMEN1SLC22A1ALDH1A1 | |
| SCHEMBL3250064 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2DHFRMEN1SLC22A1ALDH1A1 | |
| SCHEMBL5657657 | 0.81 | DHFR (0.47) | SMN1; SMN2DHFRMEN1SLC22A1ALDH1A1 | |
| SCHEMBL14140118 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2DHFRMEN1SLC22A1ALDH1A1 | |
| SCHEMBL6003796 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2DHFRMEN1SLC22A1ALDH1A1 | |
| SCHEMBL3255329 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2DHFRMEN1SLC22A1ALDH1A1 | |
| SCHEMBL14140130 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2DHFRMEN1SLC22A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161561-A1 | Novel Processing for the Preparation of a Benzofuran | ARPIDA (CH) | 2008-07-03 | — | — | US | disclosed |
| US-20080161561-A1 | Novel Processing for the Preparation of a Benzofuran | ARPIDA (CH) | 2008-07-03 | — | — | US | disclosed |
| US-20080161561-A1 | Novel Processing for the Preparation of a Benzofuran | ARPIDA (CH) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161561-A1 | Novel Processing for the Preparation of a Benzofuran | DHFR, DHPS, DPYD | SMN1; SMN2 2926/4885DHFR 1/4885MEN1 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.