Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2959879 | 0.89 | ALDH1A1 (0.42) | ALDH1A1CACNA1BAPBA1NPC1HDAC1 | |
| SCHEMBL2953712 | 0.83 | POLB (0.45) | ALDH1A1CACNA1BAPBA1NPC1HDAC1 | |
| SCHEMBL2947686 | 0.81 | ALDH1A1 (0.51) | ALDH1A1NPC1GAAMAPTSMN1; SMN2 | |
| SCHEMBL2959960 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CACNA1BAPBA1NPC1KMT2A | |
| SCHEMBL2958478 | 0.80 | NPSR1 (0.43) | ALDH1A1HDAC1KMT2AMEN1HDAC3 | |
| SCHEMBL5635601 | 0.79 | MAPT (0.42) | ALDH1A1NPC1KMT2AMEN1GAA | |
| SCHEMBL2951453 | 0.78 | ALDH1A1 (0.43) | ALDH1A1CACNA1BAPBA1HDAC1KMT2A | |
| SCHEMBL2951160 | 0.77 | MAPT (0.37) | ALDH1A1CACNA1BAPBA1NPC1KMT2A | |
| SCHEMBL2950804 | 0.73 | MAPT (0.36) | ALDH1A1CACNA1BAPBA1MAPTL3MBTL1 | |
| SCHEMBL2951297 | 0.72 | ALDH1A1 (0.43) | ALDH1A1NPC1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653259-B2 | Process for synthesizing heterocyclic compounds | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-02-18 | — | — | US | disclosed |
| US-20080146797-A1 | PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
| US-20040242560-A1 | Process for synthesizing heterocyclic compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146797-A1 | PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS | TST, NISCH, CLIC4 | ALDH1A1 406/4885CACNA1B 1508/4885APBA1 2307/4885 |
| US-20040242560-A1 | Process for synthesizing heterocyclic compounds | TST, NISCH, CLIC4 | ALDH1A1 317/4885CACNA1B 1066/4885APBA1 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.