⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296017 | 1.00 | — | — | |
| SCHEMBL5132326 | 1.00 | CES2 (0.42) | — | |
| Hydrochloric Acid SCHEMBL27295259 | 0.97 | CES2 (0.41) | — | |
| SCHEMBL27276040 | 0.97 | CES2 (0.41) | — | |
| SCHEMBL23880732 | 0.84 | — | — | |
| SCHEMBL180426 | 0.77 | — | — | |
| SCHEMBL1967992 | 0.77 | — | — | |
| SCHEMBL19056 | 0.75 | — | — | |
| SCHEMBL31729513 | 0.75 | — | — | |
| SCHEMBL5132980 | 0.75 | ACHE (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113382717-A | Use of topical BRAF inhibitor compositions for the treatment of radiodermatitis | 鲁特里斯制药有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-110404587-A | A kind of support type cluster catalyst and its preparation and application | UNIV ANHUI | 2019-11-05 | — | — | CN | claimed |
| CN-103066326-A | Electrolyte for chargeable magnesium battery | UNIV SHANGHAI JIAOTONG | 2013-04-24 | — | — | CN | claimed |
| US-8198378-B2 | Aromatic organosulfur functionalized 1,4-cis polybutadiene | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-06-12 | — | — | US | claimed |
| US-20110136956-A1 | 1,4-CIS-POLYBUTADIENE FUNCTIONALIZED WITH ORGANOSULFUR COMPOUND FOR PREPARATION OF GOLF BALL CORE | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2011-06-09 | — | — | US | claimed |
| US-20090156751-A1 | Aromatic Organosulfur Functionalized 1,4-cis Polybutadiene | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2009-06-18 | — | — | US | claimed |
| US-5290911-A | Forming polymers by catalytic oxidative coupling | RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) | 1994-03-01 | — | — | US | claimed |
| US-12565476-B2 | 2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric SHP2 inhibitors | Revolution Medicines, Inc. (US) | 2026-03-03 | — | — | US | disclosed |
| EP-4648763-A2 | COMPOUNDS FOR FGFRS INHIBITORS | Cogent Biosciences, Inc. (US) | 2025-11-19 | — | — | EP | disclosed |
| US-20240270741-A1 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. | 2024-08-15 | — | — | US | disclosed |
| WO-2024151638-A2 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20240116878-A1 | 2,5-DISUBSTITUTED 3-METHYL PYRAZINES AND 2,5,6-TRISUBSTITUTED 3-METHYL PYRAZINES AS ALLOSTERIC SHP2 INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2024-04-11 | — | — | US | disclosed |
| EP-4302834-A2 | 2,5-DISUBSTITUTED 3-METHYL PYRAZINES AND 2,5,6-TRISUBSTITUTED 3-METHYL PYRAZINES AS ALLOSTERIC SHP2 INHIBITORS | Revolution Medicines, Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| US-4931542-A | Process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL COMPANY, LIMITED (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0277194-A4 | OLEFIN OLIGOMERIZATION PROCESS AND CATALYST. | CHEVRON RES (US) | 1988-11-23 | — | — | EP | disclosed |
| EP-0281036-A2 | A process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |
| EP-0277194-A1 | OLEFIN OLIGOMERIZATION PROCESS AND CATALYST. | CHEVRON RES (US) | 1988-08-10 | — | — | EP | disclosed |
| US-4757042-A | Complex of nickel and palladium with fluoroorganic thiol or sulfide ligand and borohydride or organoaluminum halide or alkoxide | CHEVRON RESEARCH COMPANY (US) | 1988-07-12 | — | — | US | disclosed |
| WO-1988001261-A1 | OLEFIN OLIGOMERIZATION PROCESS AND CATALYST | CHEVRON RESEARCH COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |
| US-4677241-A | USING TRANSITION METAL COMPLEX CATALYST AND ORGANOMETALLIC REDUCING AGENT | CHEVRON RESEARCH COMPANY (US) | 1987-06-30 | — | — | US | disclosed |