⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1674926 | 0.77 | — | — | |
| SCHEMBL6263401 | 0.76 | — | — | |
| SCHEMBL14079969 | 0.75 | — | — | |
| SCHEMBL22991924 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL20067531 | 0.71 | — | — | |
| SCHEMBL25769 | 0.70 | — | — | |
| SCHEMBL25768 | 0.70 | — | — | |
| SCHEMBL13308198 | 0.70 | — | — | |
| SCHEMBL22825579 | 0.70 | EGFR (0.43) | — | |
| SCHEMBL25762048 | 0.70 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221303-A1 | Method for the Preparation of Peptide-Oligonucleotide Conjugates | FRUTAROM LTD. (IL) | 2008-09-11 | — | — | US | disclosed |
| EP-1725250-A2 | METHOD FOR THE PREPARATION OF PEPTIDE-OLIGONUCLEOTIDE CONJUGATES | FRUTAROM LTD. (IL) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005076744-A2 | METHOD FOR THE PREPARATION OF PEPTIDE-OLIGONUCLEOTIDE CONJUGATES | FRUTAROM LTD. (IL) | 2005-08-25 | — | — | WO | disclosed |