Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457558 | 0.88 | POLB (0.46) | PTGS1POLBGAAGFERALDH1A1 | |
| SCHEMBL31307331 | 0.88 | CA12 (0.39) | POLBGAAGFERHSD17B10ALDH1A1 | |
| SCHEMBL458456 | 0.88 | CA12 (0.39) | POLBGAAGFERHSD17B10ALDH1A1 | |
| Bromide SCHEMBL454874 | 0.86 | CA12 (0.38) | POLBGAAGFERHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL454032 | 0.86 | CA12 (0.38) | POLBGAAGFERHSD17B10ALDH1A1 | |
| SCHEMBL457069 | 0.84 | PTGS1 (0.40) | PTGS1POLBGAAGFERHSD17B10 | |
| Acetic Acid SCHEMBL457559 | 0.83 | CA12 (0.39) | PTGS1POLBGAAGFERALDH1A1 | |
| SCHEMBL457070 | 0.83 | PTGS1 (0.49) | PTGS1POLBGAAGFERHSD17B10 | |
| Hydrochloric Acid SCHEMBL19438009 | 0.73 | MEN1 (0.47) | POLBGAAGFERALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8640344 | 0.71 | ALOX5 (0.40) | HSD17B10ALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031796-A2 | AGENTS FOR COLOURING KERATINIC FIBRES WITH CATIONIC DERIVATIVES OF 1-(2,5-DIHYDROXYPHENYL)PYRIDINIUM | HENKEL AG & CO. KGAA (DE) | 2012-03-15 | — | — | WO | disclosed |