Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31307331 | 0.98 | CA12 (0.39) | CA12CA2CA9CA14ALOX5 | |
| SCHEMBL458456 | 0.98 | CA12 (0.39) | CA12CA2CA9CA14ALOX5 | |
| Bromide SCHEMBL454874 | 0.96 | CA12 (0.38) | CA12CA2CA9CA14ALOX5 | |
| Sulfuric Acid SCHEMBL457707 | 0.86 | PTGS1 (0.43) | CA12CA2CA9CA14ALOX5 | |
| Acetic Acid SCHEMBL457559 | 0.86 | CA12 (0.39) | CA12CA2CA9CA14ALOX5 | |
| Hydrochloric Acid SCHEMBL8640344 | 0.83 | ALOX5 (0.40) | CA12CA2CA9CA14ALOX5 | |
| Hydrochloric Acid SCHEMBL31307327 | 0.81 | GUSB (0.45) | ALOX5PTGS2ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL457558 | 0.81 | POLB (0.46) | CA12CA2CA9CA14CA1 | |
| Hydrochloric Acid SCHEMBL31307333 | 0.80 | ACHE (0.39) | CA12CA2CA9CA14CA1 | |
| Hydrochloric Acid SCHEMBL19438009 | 0.78 | MEN1 (0.47) | CA12CA2CA9CA14ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691122-A | REDOX SYSTEMS, COCATALYSTS, REHALOGENATION | EASTMAN KODAK COMPANY (US) | 1997-11-25 | — | — | US | claimed |
| US-5656416-A | REVERSE REDOX COUPLE; SYNERGISTIC BLEACHING | EASTMAN KODAK COMPANY (US) | 1997-08-12 | — | — | US | claimed |
| US-5510232-A | PRETREATING EXPOSED AND DEVELOPED FILM WITH CATIONIC HYDROQUINONE SOLUTION BEFORE BLEACHING | EASTMAN KODAK COMPANY (US) | 1996-04-23 | — | — | US | claimed |
| WO-2012031796-A2 | AGENTS FOR COLOURING KERATINIC FIBRES WITH CATIONIC DERIVATIVES OF 1-(2,5-DIHYDROXYPHENYL)PYRIDINIUM | HENKEL AG & CO. KGAA (DE) | 2012-03-15 | — | — | WO | disclosed |
| US-5776665-A | BLEACH PROMOTERS FOR PHOTOGRAPHIC FILMS | EASTMAN KODAK COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| US-5691122-A | REDOX SYSTEMS, COCATALYSTS, REHALOGENATION | EASTMAN KODAK COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| US-5656416-A | REVERSE REDOX COUPLE; SYNERGISTIC BLEACHING | EASTMAN KODAK COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| US-5510232-A | PRETREATING EXPOSED AND DEVELOPED FILM WITH CATIONIC HYDROQUINONE SOLUTION BEFORE BLEACHING | EASTMAN KODAK COMPANY (US) | 1996-04-23 | — | — | US | disclosed |