SCHEMBL4577202

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4577207	0.86	ALDH1A1 (0.40)	ALDH1A1ATMNPC1RAB9AGNAI3
	SCHEMBL12436975	0.79	NPC1 (0.39)	ALDH1A1ATMNPC1RAB9ASMN1; SMN2
	SCHEMBL27240732	0.77	NPC1 (0.38)	ALDH1A1ATMNPC1RAB9AHSD17B10
	SCHEMBL4578708	0.77	EPHX2 (0.50)	ALDH1A1NPC1GNAI3GNAO1GNAI1
	SCHEMBL11241398	0.75	ALDH1A1 (0.49)	ALDH1A1ATMHSD17B10POLBSMN1; SMN2
	SCHEMBL12520053	0.75	ALDH1A1 (0.53)	ALDH1A1ATMHSD17B10POLBSMN1; SMN2
	SCHEMBL4578079	0.74	ITGB3 (0.43)	ALDH1A1NPC1GNAI3GNAO1GNAI1
	SCHEMBL18016684	0.73	CYP1A2 (0.46)	ALDH1A1POLBSMN1; SMN2KMT2AL3MBTL1
	SCHEMBL4578051	0.72	CYP1A2 (0.44)	SMN1; SMN2
	SCHEMBL3549604	0.72	ALDH1A1 (0.36)	ALDH1A1ATMNPC1RAB9AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.