Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 16/20 | 0.62 |
| ▸ | MC4R | P32245 | 4/20 | 0.58 |
| ▸ | MC3R | P41968 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27392877 | 0.81 | MC4R (0.73) | PRCPMC4RMC3R | |
| SCHEMBL5673897 | 0.80 | PRCP (0.64) | PRCPMC4RMC3R | |
| SCHEMBL5617397 | 0.80 | MC4R (0.67) | PRCPMC4RMC3R | |
| SCHEMBL4577060 | 0.80 | MC4R (0.71) | PRCPMC4RMC3R | |
| SCHEMBL4577067 | 0.80 | MC4R (0.71) | PRCPMC4RMC3R | |
| SCHEMBL4577252 | 0.80 | MC4R (0.60) | PRCPMC4RMC3R | |
| SCHEMBL4577231 | 0.80 | PRCP (0.63) | PRCPMC4RMC3R | |
| SCHEMBL4577262 | 0.79 | PRCP (0.58) | PRCPMC4RMC3R | |
| SCHEMBL4591654 | 0.79 | PRCP (0.62) | PRCPMC4RMC3R | |
| SCHEMBL4958465 | 0.79 | MC4R (0.63) | PRCPMC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534074-A4 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY | MERCK & CO INC (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1534074-A2 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY | Merck & Co., Inc. (US) | 2005-06-01 | — | — | EP | claimed |
| WO-2004009015-A2 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY | MERCK & CO., INC. (US) | 2004-01-29 | — | — | WO | claimed |