Sugi Predict

Sugi Predict / Compounds / SCHEMBL4577246

SCHEMBL4577246

SCHEMBL4577246

Cc1cccc2c1C(O)(O)c1ccccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 11/20 0.47
▸ CA1 P00915 2/20 0.44
▸ CA2 P00918 2/20 0.44
▸ CA7 P43166 2/20 0.44
▸ CA9 Q16790 2/20 0.44
▸ THRB P10828 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ ESR1 P03372 1/20 0.41
▸ ESR2 Q92731 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.37
▸ TSHR P16473 2/20 0.37
▸ ALOX12 P18054 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ CASP1 P29466 1/20 0.37
▸ RECQL P46063 1/20 0.37
▸ BACE1 P56817 1/20 0.37
▸ EHMT2 Q96KQ7 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ MYC P01106 1/20 0.36
▸ ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19577694 0.78 ESR1 (0.47) PDK2THRBTDP1ESR1ESR2
SCHEMBL7315929 0.77 PDK2 (0.42) PDK2CA1CA2CA7CA9
SCHEMBL24933869 0.77 PDK2 (0.41) PDK2ESR1ESR2ALDH1A1TSHR
SCHEMBL4325901 0.77 PDK2 (0.56) PDK2CA1CA2CA7CA9
SCHEMBL30899336 0.77 PDK2 (0.56) PDK2CA1CA2CA7CA9
SCHEMBL14421863 0.76 PDK2 (0.41) PDK2CA1CA2CA7CA9
SCHEMBL8094339 0.76 THRB (0.67) PDK2CA1CA2CA7CA9
SCHEMBL18819964 0.75 PDK2 (0.40) PDK2CA1CA2CA7CA9
SCHEMBL7045215 0.75 PDK2 (0.43) PDK2CA1CA2CA7CA9
SCHEMBL30741411 0.75 THRB (0.50) PDK2CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820522-B Olefin polymerization catalyst, preparation method and application 淄博新塑化工有限公司 2024-05-17 — — CN claimed
CN-117820522-A Olefin polymerization catalyst, preparation method and application 淄博新塑化工有限公司 2024-04-05 — — CN claimed
CN-117820522-B Olefin polymerization catalyst, preparation method and application 淄博新塑化工有限公司 2024-05-17 — — CN disclosed
CN-117820522-B Olefin polymerization catalyst, preparation method and application 淄博新塑化工有限公司 2024-05-17 — — CN disclosed
CN-117820522-A Olefin polymerization catalyst, preparation method and application 淄博新塑化工有限公司 2024-04-05 — — CN disclosed
CN-117820522-A Olefin polymerization catalyst, preparation method and application 淄博新塑化工有限公司 2024-04-05 — — CN disclosed
CN-116514863-A Hydroxy protection and deprotection method of 9-fluorenylmethanol 太原理工大学 2023-08-01 — — CN disclosed
CN-112898130-B Method for synthesizing 9-fluorenylmethanol with high selectivity 太原理工大学 2023-05-16 — — CN disclosed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 — — EP disclosed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 — — US disclosed
EP-1472293-A4 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2008-01-16 — — EP disclosed
EP-1478617-A4 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2006-04-19 — — EP disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 — — US disclosed
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL (CN) 2005-05-05 — — US disclosed
EP-1478617-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-24 — — EP disclosed
EP-1472293-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-03 — — EP disclosed
WO-2003068828-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 — — WO disclosed
WO-2003068723-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CBR3, CBR1, OXER1 PDK2 1852/4885CA1 571/4885CA2 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.