Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 16/20 | 0.74 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576687 | 0.91 | CCR3 (0.71) | CCR3HTR2A | |
| SCHEMBL4578306 | 0.88 | KDM4E (0.64) | CCR3ALDH1A1LMNA | |
| SCHEMBL6701753 | 0.85 | CCR3 (1.00) | CCR3HTR2A | |
| SCHEMBL28599359 | 0.85 | KDM4E (0.71) | CCR3ALDH1A1LMNA | |
| SCHEMBL4578859 | 0.84 | ALDH1A1 (0.67) | CCR3ALDH1A1LMNA | |
| SCHEMBL6704422 | 0.84 | CCR3 (0.89) | CCR3HTR2A | |
| SCHEMBL5346262 | 0.84 | CCR3 (0.70) | CCR3HTR2A | |
| Hydrochloric Acid SCHEMBL4576674 | 0.84 | ALDH1A1 (0.66) | CCR3ALDH1A1LMNA | |
| SCHEMBL13490093 | 0.84 | ALDH1A1 (0.66) | CCR3ALDH1A1LMNA | |
| SCHEMBL4577506 | 0.83 | CCR3 (0.68) | CCR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435744-B2 | Piperidine derivatives as NMDA receptor antagonists | GEDEON RICHTER VEGYESZETI GYAR RT (HU) | 2008-10-14 | — | — | US | disclosed |
| US-20040157886-A1 | Piperdine derivatives as NMDA receptor antagonists | UCB Biopharma SRL (BE) | 2004-08-12 | — | — | US | disclosed |
| EP-1409477-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003010159-A1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157886-A1 | Piperdine derivatives as NMDA receptor antagonists | GRIN1, GRIN2D, GRIN2C | CCR3 672/4885HTR2A 342/4885ALDH1A1 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.