SCHEMBL457732

SCHEMBL457732

CCOC(=O)C(F)C(=O)C(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
LMNA P02545 2/20 0.40
HSD17B10 Q99714 1/20 0.40
ALOX15 P16050 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
TRPA1 O75762 1/20 0.36
PIN1 Q13526 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
KMT2A Q03164 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
CAD P27708 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
CPB2 Q96IY4 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7406646 0.98 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10ALOX15MGAM
Water SCHEMBL10546271 0.98 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL223479 0.85 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL28152714 0.84 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL6320653 0.82 HCAR2 (0.36) ALDH1A1LMNAHCAR2MAPT
SCHEMBL238384 0.79
SCHEMBL5074743 0.79 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL28924654 0.79 ALDH1A1 (0.48) ALDH1A1LMNAL3MBTL1HCAR2MAPT
SCHEMBL8923960 0.78 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL250103 0.78 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10ALOX15MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 898 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036534-A Synthetic method and raw material recovery method of enamine compound 山东潍坊润丰化工股份有限公司 2026-05-15 CN claimed
CN-120149502-A Secondary battery 珠海冠宇电池股份有限公司 2025-06-13 CN claimed
CN-119930957-A Trifluoro acetyl piperazine modified polyarylpiperidine film, preparation method thereof and application thereof in neutral organic flow battery 中盐金坛盐化有限责任公司 2025-05-06 CN claimed
CN-116410138-B Pyricularia sulfone Synthesis method of intermediate 山东润博生物科技有限公司 2025-05-06 CN claimed
CN-115850178-B Preparation method of 1-methyl-3- (trifluoromethyl) -1H-pyrazol-5-ol 宁夏格瑞精细化工有限公司 2025-04-04 CN claimed
CN-119463802-A Room temperature vulcanized silicone sealant for yellowing-resistant bulb lamp and preparation method thereof 宁波聚力新材料科技有限公司 2025-02-18 CN claimed
CN-119318925-A Continuous production system and continuous production method of 5- (difluoromethoxy) -4-chloromethyl-1-methyl-3- (trifluoromethyl) -1H-pyrazole 天津凯莱英医药科技发展有限公司 2025-01-17 CN claimed
CN-118988201-A Production method and equipment of ethyl trifluoroacetoacetate 济南万兴达化工有限公司 2024-11-22 CN claimed
CN-118955469-A Pyrazole alcohol compound as well as preparation method and application thereof 安徽中医药大学 2024-11-15 CN claimed
CN-118834189-A Light-induced fluorescence excitation probe, indazolone compound, and preparation methods and applications thereof 国科大杭州高等研究院 2024-10-25 CN claimed
EP-0135491-B1 HERBICIDAL 2,6-BIS-FLUOROMETHYL-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS MONSANTO COMPANY (US) 1989-01-25 EP claimed
EP-0158399-B1 LIQUID COATING COMPOSITION FOR PRODUCING HIGH QUALITY, HIGH PERFORMANCE FLUORINE-DOPED TIN OXIDE COATINGS M & T CHEMICALS, INC. (US) 1988-11-02 EP claimed
EP-0206953-B1 PROCESS FOR THE PREPARATION OF ETHYL TRIFLUOROACETOACETATE RHONE-POULENC CHIMIE (FR) 1988-09-07 EP claimed
EP-0270724-A1 Preparation of alkyl trifluoroacetoacetate Monsanto Company (US) 1988-06-15 EP claimed
US-4731256-A Liquid coating composition for producing high quality, high performance fluorine-doped tin oxide coatings M&T CHEMICALS INC. (US) 1988-03-15 US claimed
US-4696837-A Chemical vapor deposition method of producing fluorine-doped tin oxide coatings M&T CHEMICALS INC. (US) 1987-09-29 US claimed
US-4647689-A Preparation of alkyl trifluoroacetoacetate MONSANTO COMPANY (US) 1987-03-03 US claimed
US-4601917-A CHEMICAL VAPOR DEPOSITION M&T CHEMICALS INC. (US) 1986-07-22 US claimed
EP-0135491-A1 Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters MONSANTO COMPANY (US) 1985-03-27 EP claimed
US-4026898-A 7-Oxo-1,2,3,3,8-pentamethyl-5-trifluoromethyl-2,3,7,8-tetrahydro-1-H-pyrrolo[3,2-g]q THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-05-31 US claimed