SCHEMBL4577367

SCHEMBL4577367

Cc1ccccc1C(O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.54
ACHE P22303 2/20 0.47
TSHR P16473 1/20 0.47
GAA P10253 1/20 0.47
ACP3 P15309 1/20 0.45
ALDH1A1 P00352 3/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
CYP3A4 P08684 2/20 0.39
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
CYP2D6 P10635 1/20 0.39
KCNH2 Q12809 1/20 0.39
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
OPRK1 P41145 1/20 0.38
OPRL1 P41146 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13993318 0.88 ESR1 (0.59) ESR1ACHETSHRGAAACP3
Glycerin SCHEMBL15914143 0.87 CYP1A2 (0.50) ESR1ACHETSHRGAAACP3
SCHEMBL30507724 0.86 ESR1 (0.56) ESR1ACHETSHRGAAACP3
SCHEMBL598722 0.83 GAA (0.57) ESR1ACHETSHRGAAACP3
SCHEMBL3073519 0.81 ESR1 (0.52) ESR1ACHETSHRGAAACP3
SCHEMBL342736 0.81 ESR1 (0.52) ESR1ACHETSHRGAAACP3
SCHEMBL231827 0.81 ESR1 (0.52) ESR1ACHETSHRGAAACP3
SCHEMBL17446315 0.79 ESR1 (0.50) ESR1ACHETSHRGAAACP3
SCHEMBL14040083 0.79 ESR1 (0.50) ESR1ACHETSHRGAAACP3
SCHEMBL17446316 0.79 ESR1 (0.50) ESR1ACHETSHRGAAACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502372-A1 4-tert-Alkyl-2-Methylbenzaldehydedialkylacetals BASF Aktiengesellschaft (DE) 1992-09-09 EP claimed
CN-118995087-A Adhesive film and dicing film-die bonding film 株式会社力森诺科 2024-11-22 CN disclosed
CN-118053799-A Method for manufacturing semiconductor device 株式会社力森诺科 2024-05-17 CN disclosed
CN-117157733-A Method for manufacturing semiconductor device and dicing die-bonding integrated film 株式会社力森诺科 2023-12-01 CN disclosed
CN-110945634-B Heat-dissipating die bonding film and dicing die bonding film 株式会社力森诺科 2023-08-29 CN disclosed
CN-112292431-B Crystal cutting and crystal bonding integrated film and pressure-sensitive adhesive film used by same 昭和电工材料株式会社 2022-09-02 CN disclosed
US-10577346-B2 Benzobicycloalkane derivatives, their preparation and pharmaceutical use thereof SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2020-03-03 US disclosed
WO-2019135136-A1 COORDINATION COMPLEXES HAVING MICROBIAL ACTIVITY AND INCORPORABLE IN HYALURONIC ACID COMPOSITIONS LAB SRL (IT) 2019-07-11 WO disclosed
US-20190161468-A1 BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2019-05-30 US disclosed
CN-108238996-A The synthetic method of drug synthesis intermediate P―Carboxybenzenesulfonamide 成都切斯特科技有限公司 2018-07-03 CN disclosed
US-20100196319-A1 4, 5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS SCHERING CORPORATION (US) 2010-08-05 US disclosed
EP-1553450-B1 Process for preparing plugged-through-hole printed wiring board and plugged-through-hole printed wiring board SAN EI KAGAKU CO (JP) 2010-05-26 EP disclosed
US-20080070303-A1 Using myocardial and/or muscle progenitor cells as modeling tool in tissue engineering; regenerative medicine and organ replacement ADVANCED CELL TECHNOLOGY 2008-03-20 US disclosed
EP-1472293-A4 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2008-01-16 EP disclosed
WO-2005041904-A2 INHIBITORS OF CORONAVIRUS PROTEASE AND METHODS OF USE THEREOF FULCRUM PHARMACEUTICALS, INC. (US) 2005-05-12 WO disclosed
EP-1472293-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-03 EP disclosed
WO-2003068828-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed
JP-2000095777-A PRODUCTION OF ALPHA, ALPHA'-DISUBSTITUTED XYLENE SHOWA DENKO KK 2000-04-04 JP disclosed
US-5236934-A Angiotensin inhibitors E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-17 US disclosed
EP-0311387-A2 Aromatic amine resins, their production process and thermosetting resin compositions making use of the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100196319-A1 4, 5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS ZC3HAV1, IDO1, ZC3HAV1L ESR1 2725/4885ACHE 1763/4885TSHR 1385/4885
US-20190161468-A1 BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF CYP3A7, CYP2A7, CYP2J2 ESR1 2384/4885ACHE 713/4885TSHR 4624/4885
US-10577346-B2 Benzobicycloalkane derivatives, their preparation and pharmaceutical use thereof CYP3A7, UGT2B7, BDKRB1 ESR1 2766/4885ACHE 300/4885TSHR 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.