Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16862173 | 0.75 | MAOA (0.46) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL29440783 | 0.74 | MAOA (0.38) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL12567731 | 0.72 | MAOA (0.43) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL29694162 | 0.71 | MAOA (0.42) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL28873116 | 0.71 | MAOA (0.42) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL7654573 | 0.68 | MAOA (0.43) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL3490518 | 0.67 | MAOA (0.46) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL9031787 | 0.65 | MAOA (0.50) | MAOAMAOBGAANPSR1TSHR | |
| SCHEMBL971330 | 0.64 | MAOA (0.70) | MAOAMAOBGAANPSR1TSHR | |
| Xanthene SCHEMBL4267 | 0.64 | MAOA (1.00) | MAOAMAOBGAANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576536-A2 | HAEMATOPOIETIC-PROSTAGLANDIN D2 SYNTHASE INHIBITORS | The University of Queensland (AU) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011150457-A2 | HAEMATOPOIETIC-PROSTAGLANDIN D2 SYNTHASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2011-12-08 | — | — | WO | disclosed |