Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.70 |
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360775 | 1.00 | MAOA (0.70) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL4500547 | 0.89 | MAOA (0.64) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL7295118 | 0.83 | MAOA (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL13950592 | 0.83 | MAOA (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL29586724 | 0.83 | MAOA (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL11096945 | 0.83 | HTR2C (0.65) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL5733780 | 0.83 | MAOA (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| SCHEMBL12773597 | 0.83 | MAOA (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| Dihydrocoumarin SCHEMBL28795 | 0.83 | MAOB (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| Dihydrocoumarin SCHEMBL17629427 | 0.83 | MAOB (0.50) | MAOAMAOBGAANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217967-A | Tricyclic antidepressant co-administered with a N-benzylpyrrolidin-2-one | BOEHRINGER INGELHEIM GMBH (DE) | 1993-06-08 | — | — | US | claimed |
| EP-0280290-B1 | AGENT HAVING AN ANTIDEPRESSIVE ACTIVITY | BOEHRINGER INGELHEIM KG (DE) | 1992-01-08 | — | — | EP | claimed |
| US-4931435-A | TRICYCLIC ANTIDEPRESSANT WITH BENZYLPYRROLIDINONE; SIDE EFFECT REDUCTION | BOEHRINGER INGELHEIM KG (DE) | 1990-06-05 | — | — | US | claimed |
| EP-0280290-A2 | Agent having an antidepressive activity | BOEHRINGER INGELHEIM KG (DE) | 1988-08-31 | — | — | EP | claimed |
| US-11829036-B2 | Optically anisotropic multilayer product and method for producing same | ZEON CORPORATION (JP) | 2023-11-28 | — | — | US | disclosed |
| US-11829036-B2 | Optically anisotropic multilayer product and method for producing same | ZEON CORPORATION (JP) | 2023-11-28 | — | — | US | disclosed |
| US-11697695-B2 | Polymerizable composition and optically anisotropic body using same | DIC CORPORATION (JP) | 2023-07-11 | — | — | US | disclosed |
| US-11697695-B2 | Polymerizable composition and optically anisotropic body using same | DIC CORPORATION (JP) | 2023-07-11 | — | — | US | disclosed |
| US-20230137250-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE | DAI NIPPON PRINTING CO., LTD. (JP) | 2023-05-04 | — | — | US | disclosed |
| US-20230137250-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE | DAI NIPPON PRINTING CO., LTD. (JP) | 2023-05-04 | — | — | US | disclosed |
| US-11560518-B2 | Polymerizable liquid crystal compound, polymerizable composition, polymer, retardation film, method for producing retardation film, transfer laminate, optical member, method for producing optical member, and display device | DAI NIPPON PRINTING CO., LTD. (JP) | 2023-01-24 | — | — | US | disclosed |
| US-20210380884-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE | DAI NIPPON PRINTING CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
| EP-0607864-A2 | Tricyclic condensed heterocyclic compounds for the treatment of senile dementic | Takeda Chemical Industries, Ltd. (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5217967-A | Tricyclic antidepressant co-administered with a N-benzylpyrrolidin-2-one | BOEHRINGER INGELHEIM GMBH (DE) | 1993-06-08 | — | — | US | disclosed |
| US-5216178-A | Contacting with alkaline earth metal and lower alkanol | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-06-01 | — | — | US | disclosed |
| US-5140027-A | Antidepressants, analgesics and anticonvulsants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-08-18 | — | — | US | disclosed |
| US-4943571-A | ANALGESICS, ANTICONVULSANTS, ANTIDEPRESSANTS | HOECHST-ROUSSEL PHAMRACEUTICALS INC. (US) | 1990-07-24 | — | — | US | disclosed |
| US-4931435-A | TRICYCLIC ANTIDEPRESSANT WITH BENZYLPYRROLIDINONE; SIDE EFFECT REDUCTION | BOEHRINGER INGELHEIM KG (DE) | 1990-06-05 | — | — | US | disclosed |
| US-4837227-A | ANALGESICS, ANTIDEPRESSANTS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0280290-A2 | Agent having an antidepressive activity | BOEHRINGER INGELHEIM KG (DE) | 1988-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137250-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE | TRRAP, CDH1, LRRFIP1 | MAOA 3001/4885MAOB 3007/4885GAA 3970/4885 |
| US-11560518-B2 | Polymerizable liquid crystal compound, polymerizable composition, polymer, retardation film, method for producing retardation film, transfer laminate, optical member, method for producing optical member, and display device | TRRAP, CDH1, LRRFIP1 | MAOA 3001/4885MAOB 3007/4885GAA 3970/4885 |
| US-20210380884-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE | TRRAP, CDH1, LRRFIP1 | MAOA 3001/4885MAOB 3007/4885GAA 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.