Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28702129 | 0.92 | TSHR (0.56) | TSHRDAONAPRTADRA2CCHRM2 | |
| Benzoic Acid SCHEMBL1082233 | 0.92 | TSHR (0.56) | TSHRDAONAPRTADRA2CCHRM2 | |
| Benzoyl Formic Acid SCHEMBL16045766 | 0.92 | CES2 (0.47) | TSHRDAONAPRTADRA2CCHRM2 | |
| Benzoic Acid SCHEMBL16045040 | 0.88 | ALDH1A1 (0.48) | TSHRDAONAPRTADRA2CCHRM2 | |
| Benzoic Acid SCHEMBL16045171 | 0.88 | KDM4E (0.41) | TSHRDAONAPRTADRA2CCHRM2 | |
| Benzoic Acid SCHEMBL4591805 | 0.86 | TSHR (0.64) | TSHRDAONAPRTCYP3A4CYP2C9 | |
| Benzoic Acid SCHEMBL27522795 | 0.86 | TSHR (0.64) | TSHRDAONAPRTCYP3A4CYP2C9 | |
| Benzoic Acid SCHEMBL570447 | 0.86 | TSHR (0.64) | TSHRDAONAPRTCYP3A4CYP2C9 | |
| SCHEMBL1080697 | 0.86 | KDM4E (0.60) | TSHRADRA2CCHRM2ADRA1ARGS12 | |
| Benzoyl Formic Acid SCHEMBL16045688 | 0.84 | CES2 (0.50) | TSHRDAONAPRTADRA2CCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596588-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2025-08-06 | — | — | EP | claimed |
| CN-117924558-A | Solid catalyst component for olefin polymerization, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117924557-A | Prepolymerized catalyst for olefin polymerization, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117924559-A | Solid catalyst component for olefin polymerization and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-112175119-B | Solid catalyst component for olefin polymerization, process for producing the same, olefin polymerization catalyst, and process for olefin polymerization | 中国石油化工股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-112175117-B | Solid catalyst component for olefin polymerization, process for producing the same, catalyst for olefin polymerization, and process for olefin polymerization | 中国石油化工股份有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-114478846-A | Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| EP-3059263-B1 | SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR | CHINA PETROLEUM & CHEM CORP (CN) | 2021-07-21 | — | — | EP | claimed |
| CN-112175117-A | Solid catalyst component for olefin polymerization and preparation method thereof, catalyst for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2021-01-05 | — | — | CN | claimed |
| CN-112175119-A | Solid catalyst component for olefin polymerization, process for producing the same, olefin polymerization catalyst, and process for olefin polymerization | 中国石油化工股份有限公司 | 2021-01-05 | — | — | CN | claimed |
| US-9951157-B2 | Spherical carriers for olefin polymerization catalyst, catalyst components, catalyst, and preparation methods therefor | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2018-04-24 | — | — | US | claimed |
| EP-1472293-B1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2017-04-26 | — | — | EP | claimed |
| US-20160251457-A1 | SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2016-09-01 | — | — | US | claimed |
| EP-3059263-A1 | SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR | China Petroleum&Chemical Corporation (CN) | 2016-08-24 | — | — | EP | claimed |
| US-9068026-B2 | Magnesium halide adducts, catalyst components and catalysts comprising the same, and preparation processes thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2015-06-30 | — | — | US | claimed |
| US-20120302708-A1 | MAGNESIUM HALIDE ADDUCTS, CATALYST COMPONENTS AND CATALYSTS COMPRISING THE SAME, AND PREPARATION PROCESSES THEREOF | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2012-11-29 | — | — | US | claimed |
| US-20050096389-A1 | Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof | CHINA PETROLEUM & CHEMICAL (CN) | 2005-05-05 | — | — | US | claimed |
| US-20250320318-A1 | OLEFIN POLYMERIZATION CATALYST COMPONENT, CATALYST SYSTEM, PREPOLYMERIZATION CATALYST COMPOSITION AND OLEFIN POLYMERIZATION METHOD | CHINA PETROLEUM & CHEM CORP (CN) | 2025-10-16 | — | — | US | disclosed |
| WO-2003068828-A1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2003-08-21 | — | — | WO | disclosed |
| WO-2003068723-A1 | POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096389-A1 | Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof | CBR3, CBR1, OXER1 | TSHR 921/4885DAO 1971/4885NAPRT 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.