Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412337 | 0.90 | LDHA (0.37) | LDHASRR | |
| SCHEMBL42019 | 0.90 | LDHA (0.37) | LDHASRR | |
| Urea SCHEMBL1253183 | 0.88 | LDHA (0.32) | GLRA1SLC6A9OR51E2LDHASRR | |
| SCHEMBL3911509 | 0.87 | LDHA (0.35) | LDHASRR | |
| SCHEMBL10490033 | 0.87 | LDHA (0.35) | LDHASRR | |
| Ammonia Solution, Strong SCHEMBL23014704 | 0.87 | LDHA (0.35) | LDHASRR | |
| Water SCHEMBL29364046 | 0.87 | LDHA (0.35) | LDHASRR | |
| SCHEMBL6130079 | 0.87 | LDHA (0.35) | LDHASRR | |
| Hydrochloric Acid SCHEMBL4920306 | 0.87 | RAB9A (0.36) | LDHASRR | |
| SCHEMBL31553566 | 0.87 | LDHA (0.35) | LDHASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171217-A1 | STABLE LIQUID ANTIBODY FORMULATION | PFIZER INC | 2011-07-14 | — | — | US | disclosed |
| EP-2331090-A1 | STABLE LIQUID ANTIBODY FORMULATION | Pfizer Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| EP-2311491-A1 | Composition comprising an antibody against macrophage colony-stimulating factor (M-CSF) and a chelating agent | Pharmacia & Upjohn Company LLC (US) | 2011-04-20 | — | — | EP | disclosed |
| US-20110027262-A1 | PLATFORM ANTIBODY COMPOSITIONS | PHARMACIA & UPJOHN COMPANY LLC | 2011-02-03 | — | — | US | disclosed |
| EP-0848251-A2 | Homogeneous on-line assays using capillary electrophoresis | BECKMAN INSTRUMENTS, INC. (US) | 1998-06-17 | — | — | EP | disclosed |