SCHEMBL4579368

SCHEMBL4579368

C=CC(=O)OCCCCc1c(C(=O)O)ccc(O)c1Cl

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.45
ALDH1A1 P00352 3/20 0.45
CYP3A4 P08684 1/20 0.45
THRB P10828 1/20 0.43
HPGD P15428 1/20 0.39
TP53 P04637 2/20 0.38
HIF1A Q16665 2/20 0.38
HSD17B10 Q99714 1/20 0.38
GAA P10253 1/20 0.34
APP P05067 4/20 0.34
BCL2L1 Q07817 1/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4578762 0.99 TSHR (0.47) TSHRALDH1A1CYP3A4THRBHPGD
SCHEMBL4577977 0.99 TSHR (0.47) TSHRALDH1A1CYP3A4THRBHPGD
SCHEMBL4579604 0.99 TSHR (0.47) TSHRALDH1A1CYP3A4THRBHPGD
SCHEMBL4578637 0.96 THRB (0.43) TSHRALDH1A1CYP3A4THRBHPGD
SCHEMBL4579244 0.91 THRB (0.46) TSHRALDH1A1CYP3A4THRBHPGD
SCHEMBL9633050 0.88 TSHR (0.55) TSHRALDH1A1CYP3A4THRBHPGD
SCHEMBL9634868 0.83 TSHR (0.52) TSHRALDH1A1CYP3A4THRBHPGD
SCHEMBL29487385 0.83 TSHR (0.49) TSHRALDH1A1CYP3A4THRBHPGD
SCHEMBL1265100 0.83 TSHR (0.49) TSHRALDH1A1CYP3A4THRBHPGD
SCHEMBL29367471 0.82 TSHR (0.51) TSHRALDH1A1CYP3A4THRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-20050187102-A1 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-08-25 US disclosed
US-6022664-A MIXTURE OF A POLYMERIZABLE VINYL MONOMER AND ORGANIC BORATE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2000-02-08 US disclosed
EP-0503674-B1 Light-sensitive bistrihalomethyl-s-triazine compound and photopolymerizable composition containing same FUJI PHOTO FILM CO LTD (JP) 1998-06-24 EP disclosed
US-5484682-A FREE RADICAL INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1996-01-16 US disclosed
US-5362874-A Storage stability, discoloration inhibition FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US disclosed
EP-0503674-A1 Light-sensitive bistrihalomethyl-S-triazine compound and photopolymerizable composition containing same FUJI PHOTO FILM CO., LTD. (JP) 1992-09-16 EP disclosed