Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489307 | 0.81 | NQO1 (0.65) | CYP2C9ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL27192968 | 0.78 | ALDH1A1 (0.63) | CYP2C9EPHX2ALDH1A1KDM4EMAPT | |
| SCHEMBL5272845 | 0.77 | CYP2C9 (0.76) | CYP2C9EPHX2ALDH1A1KDM4EMAPT | |
| SCHEMBL5273533 | 0.76 | CYP2C9 (1.00) | CYP2C9EPHX2ALDH1A1KDM4EMAPT | |
| SCHEMBL7141330 | 0.75 | CYP2C9 (0.64) | CYP2C9EPHX2ALDH1A1KDM4EMAPT | |
| SCHEMBL28961470 | 0.75 | CA12 (0.61) | CYP2C9ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL7141194 | 0.75 | CYP2C9 (0.63) | CYP2C9EPHX2ALDH1A1KDM4EMAPT | |
| SCHEMBL5905798 | 0.74 | CYP2C9 (0.79) | CYP2C9ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL27412780 | 0.72 | NQO1 (0.54) | CYP2C9ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL8489395 | 0.72 | ALDH1A1 (0.59) | CYP2C9ALDH1A1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125586-A1 | Optical molecular sensors for cytochrome P450 activity | INVITROGEN CORPORATION (US) | 2008-05-29 | — | — | US | disclosed |
| US-20070072256-A1 | OPTICAL MOLECULAR SENSORS FOR CYTOCHROME P450 ACTIVITY | INVITROGEN CORPORATION | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125586-A1 | Optical molecular sensors for cytochrome P450 activity | CYP2J2, CYP1A2, CYP2B6 | CYP2C9 21/4885EPHX2 119/4885ALDH1A1 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.