Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577933 | 1.00 | ESR1 (0.45) | ESR1ESR2GAACA12MEN1 | |
| Hydrogen Peroxide SCHEMBL8672190 | 0.87 | BCL2L1 (0.46) | CA12MEN1CA1CA2KMT2A | |
| Hydrogen Peroxide SCHEMBL8672187 | 0.87 | BCL2L1 (0.46) | CA12MEN1CA1CA2KMT2A | |
| SCHEMBL811982 | 0.87 | ESR1 (0.54) | ESR1ESR2CA12MEN1CA1 | |
| SCHEMBL9927352 | 0.87 | CES2 (0.39) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL779999 | 0.87 | CES2 (0.39) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL11991140 | 0.82 | BCL2L1 (0.46) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL78213 | 0.79 | — | — | |
| SCHEMBL18867938 | 0.79 | — | — | |
| SCHEMBL4429088 | 0.78 | ESR1 (0.71) | ESR1ESR2GAACA12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396895-B2 | Branched polyarylene ethers and processes for the preparation thereof | XEROX CORPORATION (US) | 2008-07-08 | — | — | US | disclosed |
| US-7067608-B2 | Process for preparing branched polyarylene ethers | XEROX CORPORATION (US) | 2006-06-27 | — | — | US | disclosed |
| US-20050208416-A1 | Branched polyarylene ethers and processes for the preparation thereof | XEROX CORPORATION | 2005-09-22 | — | — | US | disclosed |
| US-20050154178-A1 | Process for preparing branched polyarylene ethers | XEROX CORPORATION | 2005-07-14 | — | — | US | disclosed |