Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.62 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL672552 | 1.00 | ESR1 (0.71) | ESR1ESR2MMP3BCL2L1CA2 | |
| SCHEMBL14994124 | 0.98 | ESR1 (0.68) | ESR1ESR2MMP3BCL2L1CA2 | |
| SCHEMBL15683062 | 0.95 | ESR1 (0.65) | ESR1ESR2MMP3BCL2L1CA2 | |
| SCHEMBL29516955 | 0.95 | ESR1 (0.65) | ESR1ESR2MMP3BCL2L1CA2 | |
| SCHEMBL28397519 | 0.89 | ESR1 (0.64) | ESR1ESR2MMP3BCL2L1CA2 | |
| SCHEMBL811982 | 0.89 | ESR1 (0.54) | ESR1ESR2MMP3BCL2L1CA2 | |
| SCHEMBL14148731 | 0.88 | LTA4H (0.63) | ESR1ESR2LMNACA9CA14 | |
| Phenol SCHEMBL28217146 | 0.88 | ESR1 (0.57) | ESR1ESR2MMP3BCL2L1CA2 | |
| SCHEMBL132983 | 0.87 | LMNA (0.60) | ESR1CA2CA4LMNACA5A | |
| Triphenylphosphine Oxide SCHEMBL8431251 | 0.87 | CA2 (0.63) | ESR1CA2CA4LMNACA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621154-B | Adduct and preparation method thereof, flame retardant composition and application | 金发科技股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-113185807-B | Resin composition for underfill, electronic component device, and method for manufacturing electronic component device | 株式会社力森诺科 | 2024-03-29 | — | — | CN | claimed |
| CN-115417971-B | Flame-retardant isocyanate composite material prepared by using TDI rectifying tower kettle liquid and preparation method thereof | 万华化学集团股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-115612128-B | Multifunctional noctilucent water-based polyurethane composite board and preparation method thereof | 江苏华缘高科股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-112409599-B | Hyperbranched silicon-based resin flame retardant containing phosphorus-oxygen functionalized and preparation method thereof | 山东天一化学股份有限公司 | 2023-01-24 | — | — | CN | claimed |
| CN-115612128-A | Multifunctional noctilucent waterborne polyurethane composite board and preparation method thereof | 江苏华缘高科股份有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-115417971-A | Flame-retardant isocyanate composite material prepared from TDI (toluene diisocyanate) rectifying tower bottoms and preparation method thereof | 万华化学集团股份有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-114621154-A | Adduct and preparation method thereof, flame-retardant composition and application | 金发科技股份有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-109836817-B | Halogen flame retardant and application thereof | 杭州本松新材料技术股份有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-112480412-A | Acetoacetyl functionalized phosphorus-containing resin flame retardant and preparation method thereof | 山东天一化学股份有限公司 | 2021-03-12 | — | — | CN | claimed |
| US-7202311-B2 | Phosphine oxide hydroxyarl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CORPORATION (US) | 2007-04-10 | — | — | US | claimed |
| EP-1363922-B1 | NOVEL HYDROXYARYL PHOSPHINE OXIDES MIXTURE, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | GREAT LAKES CHEMICAL CORP (US) | 2006-07-26 | — | — | EP | claimed |
| US-20040225080-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | GREAT LAKES CHEMICAL CORPORATION | 2004-11-11 | — | — | US | claimed |
| JP-2004533413-A | — | — | 2004-11-04 | — | — | JP | claimed |
| US-20040121990-A1 | Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom | GREAT LAKES CHEMICAL CORPORATION | 2004-06-24 | — | — | US | claimed |
| US-6733698-B2 | Mixture of mono-, bis- and tris-(hydroxyaryl) phosphine oxides useful to make polyglycidyl ethers or in epoxy compositions | PABU SERVICES, INC. | 2004-05-11 | — | — | US | claimed |
| EP-1363922-A2 | NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | Pabu Services, Inc. (US) | 2003-11-26 | — | — | EP | claimed |
| US-20030148109-A1 | Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins | CHEMTURA CORPORATION | 2003-08-07 | — | — | US | claimed |
| US-20020168527-A1 | Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom | GREAT LAKES CHEMICAL CORPORATION | 2002-11-14 | — | — | US | claimed |
| WO-2002066485-A2 | NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM | PABU SERVICES, INC. (US) | 2002-08-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121990-A1 | Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom | PFAS, PTPMT1, PWWP2B | ESR1 705/4885ESR2 2057/4885MMP3 4570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.