SCHEMBL4580068

SCHEMBL4580068

C=C(C)C(=O)OCC.C=C(CC=CC(=O)O)C(=O)OCC(C)C

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.55
ALDH1A1 P00352 3/20 0.36
THRB P10828 1/20 0.36
HCAR2 Q8TDS4 1/20 0.35
CYP2D6 P10635 2/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.31
GLO1 Q04760 1/20 0.31
MAPT P10636 1/20 0.31
GPR35 Q9HC97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10589909 0.89 TSHR (0.54) TSHRALDH1A1SMN1; SMN2MAPT
SCHEMBL3165741 0.89 TSHR (0.50) TSHRALDH1A1HCAR2SMN1; SMN2MAPT
SCHEMBL5327081 0.88 TSHR (0.57) TSHRALDH1A1THRBSMN1; SMN2MAPT
SCHEMBL8678429 0.86 ALDH1A1 (0.44) TSHRALDH1A1THRBHCAR2CYP2D6
SCHEMBL9818331 0.85 TSHR (0.47) TSHRALDH1A1THRBHCAR2
Methacrylic Acid SCHEMBL4919048 0.84 HCAR2 (0.42) TSHRALDH1A1THRBHCAR2CYP2D6
SCHEMBL2023097 0.84 HCAR2 (0.47) TSHRALDH1A1HCAR2CYP2D6CYP2C19
SCHEMBL8516879 0.83 THRB (0.43) TSHRALDH1A1THRBHCAR2CYP2D6
Acrylic Acid SCHEMBL5959113 0.82 TSHR (0.68) TSHRALDH1A1THRBHCAR2CYP2D6
SCHEMBL10940121 0.82 TSHR (0.51) TSHRALDH1A1THRBHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7358032-B2 Alloy supports having recording multilayers including water insoluble and alkaline soluble polyurethanes, development inhibitors and light to heat conversion dyes, having durability and chemical resistance FUJIFILM CORPORATION (JP) 2008-04-15 US disclosed
US-20070122743-A1 comprising supports having recording layer including multilayers containing water-insoluble and alkali-soluble resin containing infrared absorbers, development inhibitors that exhibiting enhanced solubility in an aqueous alkali solution through light exposure FUJI PHOTO FILM CO., LTD. 2007-05-31 US disclosed
US-7018777-B2 Method of making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2006-03-28 US disclosed
US-20050003311-A1 Method for developing a lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-01-06 US disclosed