SCHEMBL4580118

SCHEMBL4580118

C=CC(=O)Oc1ccc(O)c(-c2nc3ccccc3s2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 15/20 0.56
MEN1 O00255 8/20 0.56
KMT2A Q03164 8/20 0.56
RAB9A P51151 7/20 0.56
KDM4E B2RXH2 6/20 0.56
NPC1 O15118 5/20 0.56
POLB P06746 5/20 0.56
GAA P10253 5/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
L3MBTL1 Q9Y468 4/20 0.56
APP P05067 1/20 0.56
THRB P10828 1/20 0.56
ALOX15 P16050 1/20 0.56
CASP1 P29466 1/20 0.56
SNCA P37840 1/20 0.56
CASP7 P55210 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
TP53 P04637 3/20 0.52
RXFP1 Q9HBX9 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12545487 0.81 RAB9A (0.59) MAPTMEN1KMT2ARAB9AKDM4E
SCHEMBL12545765 0.81 MAPT (0.62) MAPTMEN1KMT2ARAB9AKDM4E
SCHEMBL12545472 0.80 MEN1 (0.52) MAPTMEN1KMT2ARAB9AKDM4E
SCHEMBL5429408 0.80 MAPT (0.64) MAPTMEN1KMT2ARAB9AKDM4E
SCHEMBL30386590 0.80 MAPT (0.64) MAPTMEN1KMT2ARAB9AKDM4E
SCHEMBL12545647 0.77 MAPT (0.49) MAPTMEN1KMT2ARAB9AKDM4E
SCHEMBL12545479 0.77 MAPT (0.52) MAPTMEN1KMT2ARAB9AKDM4E
SCHEMBL28159221 0.76 MAPT (0.66) MAPTMEN1KMT2ARAB9AKDM4E
SCHEMBL17589055 0.75 KDM4E (0.49) MAPTMEN1KMT2ARAB9AKDM4E
SCHEMBL30172485 0.75 KDM4E (0.79) MAPTMEN1KMT2ARAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8194210-B2 Polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-06-05 US disclosed
US-20080100780-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2008-05-01 US disclosed