SCHEMBL4580147

SCHEMBL4580147

CC(=O)n1ncc2ccccc2c1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 1/20 0.50
CHEK1 O14757 1/20 0.47
AURKA O14965 1/20 0.47
DAPK3 O43293 1/20 0.47
CSNK1A1 P48729 1/20 0.47
GSK3A P49840 1/20 0.47
LIMK1 P53667 1/20 0.47
IKBKE Q14164 1/20 0.47
MAPK14 Q16539 1/20 0.47
TAOK1 Q7L7X3 1/20 0.47
CLK4 Q9HAZ1 1/20 0.47
DYRK1B Q9Y463 1/20 0.47
NPC1 O15118 7/20 0.46
RAB9A P51151 7/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.46
KMT2A Q03164 2/20 0.46
POLB P06746 2/20 0.46
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24754471 0.85 PLA2G10 (0.46) PLA2G10CHEK1AURKADAPK3CSNK1A1
SCHEMBL7365689 0.84 PLA2G10 (0.55) PLA2G10NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL10977450 0.83 PLA2G10 (0.50) PLA2G10CHEK1AURKADAPK3CSNK1A1
SCHEMBL11323086 0.82 ELANE (0.48) PLA2G10NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL11311967 0.80 PLA2G10 (0.55) PLA2G10NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL11310234 0.80 KDM4E (0.46) PLA2G10NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL31690642 0.79 CYP11B2 (0.44) PLA2G10NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL21431482 0.79 CYP11B2 (0.44) PLA2G10NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL7889097 0.78 NPC1 (0.51) PLA2G10NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1087434 0.77 CHEK1 (0.60) CHEK1AURKADAPK3CSNK1A1GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157214-B2 High-speed thermally developable imaging materials EASTMAN KODAK COMPANY (US) 2007-01-02 US claimed
US-20050069828-A1 High-speed thermally developable imaging materials EASTMAN KODAK COMPANY 2005-03-31 US claimed
US-6844145-B2 High-speed thermally developable imaging materials and methods of using same EASTMAN KODAK COMPANY (US) 2005-01-18 US claimed
US-20040009438-A1 High-speed thermally developable imaging materials and methods of using same EASTMAN KODAK COMPANY 2004-01-15 US claimed
US-7414146-B2 Imaging element containing a blocked photographically useful compound CARESTREAM HEALTH, INC. (US) 2008-08-19 US disclosed
EP-1831762-A1 BLOCKED ALIPHATIC THIOL STABILIZERS FOR PHOTOTHERMOGRAPHIC MATERIALS Carestream Health, Inc. (US) 2007-09-12 EP disclosed
EP-1735661-B1 THERMALLY DEVELOPABLE MATERIALS CONTAINING ORGANIC SILVER SALTS EASTMAN KODAK CO (US) 2007-09-05 EP disclosed
US-7214464-B2 High speed positive-working photothermographic radiographic film EASTMAN KODAK COMPANY (US) 2007-05-08 US disclosed
US-7198889-B2 High-speed positive-working photothermographic system comprising an accelerating agent EASTMAN KODAK COMPANY (US) 2007-04-03 US disclosed
EP-1315035-B1 Core/shell silver donors for photothermographic systems comprising an oxidatively less reactive shell EASTMAN KODAK CO (US) 2007-03-28 EP disclosed
US-7183024-B2 High-speed positive-working photothermographic system EASTMAN KODAK COMPANY (US) 2007-02-27 US disclosed
US-7169543-B2 Blocked aliphatic thiol stabilizers for photothermographic materials EASTMAN KODAK COMPANY (US) 2007-01-30 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed
US-4009039-A Heat developable light-sensitive oxazoline containing element FUJI PHOTO FILM CO., LTD. (JA) 1977-02-22 US disclosed
US-4003749-A Heat-developable light-sensitive materials using the reaction product of a organic silver salt an a N-halo-oxazolidinone FUJI PHOTO FILM CO., LTD. (JA) 1977-01-18 US disclosed
US-4002479-A ORGANIC SILVER SALT, SILVER HALIDE, AND A REDUCING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1977-01-11 US disclosed
US-3985565-A Photothermographic, composition using a phenolic leuco dye as a reducing agent EASTMAN KODAK COMPANY (US) 1976-10-12 US disclosed
US-3984249-A TREATING WITH HYDROGEN EASTMAN KODAK COMPANY (US) 1976-10-05 US disclosed
US-3955982-A HYDROCARBONS, HAL EASTMAN KODAK COMPANY (US) 1976-05-11 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed