Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311967 | 0.85 | PLA2G10 (0.55) | PLA2G10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4580147 | 0.84 | PLA2G10 (0.50) | PLA2G10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL10977450 | 0.84 | PLA2G10 (0.50) | PLA2G10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7366940 | 0.81 | NPC1 (0.50) | PLA2G10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11323086 | 0.80 | ELANE (0.48) | PLA2G10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL24754471 | 0.79 | PLA2G10 (0.46) | PLA2G10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11310234 | 0.78 | KDM4E (0.46) | PLA2G10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL21431482 | 0.77 | CYP11B2 (0.44) | PLA2G10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL31690642 | 0.77 | CYP11B2 (0.44) | PLA2G10NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL13799918 | 0.76 | RAB9A (0.58) | PLA2G10NPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284613-A1 | RADIOLABELLED COMPOUND | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2021-09-16 | — | — | US | disclosed |
| WO-1995009842-A1 | ISOQUINOLINONE-, PHTHALAZINONE-, QUINAZOLINONE- AND BENZOTRIAZOLINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTI-THROMBOTICS | LUITPOLD PHARMA GMBH (DE) | 1995-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284613-A1 | RADIOLABELLED COMPOUND | PARP3, PARP2, PARP1 | PLA2G10 4488/4885NPC1 2451/4885RAB9A 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.