Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581693 | 0.91 | HDAC3 (0.41) | MMP1MMP3MMP7MMP9TSHR | |
| SCHEMBL2689375 | 0.88 | HDAC3 (0.42) | MMP1MMP3MMP7MMP9ALDH1A1 | |
| SCHEMBL2689370 | 0.88 | HDAC3 (0.42) | MMP1MMP3MMP7MMP9ALDH1A1 | |
| SCHEMBL4579620 | 0.88 | HDAC3 (0.40) | MMP1MMP3MMP7MMP9ALDH1A1 | |
| SCHEMBL4581990 | 0.85 | HDAC3 (0.41) | MMP1MMP3MMP7MMP9ALDH1A1 | |
| SCHEMBL2443344 | 0.81 | AADAT (0.43) | MMP1MMP9SMN1; SMN2TP53MMP13 | |
| SCHEMBL4579581 | 0.78 | ABL1 (0.45) | MMP1MMP3MMP7MMP9KDM4E | |
| SCHEMBL4582276 | 0.77 | HDAC3 (0.41) | MMP1MMP3MMP7MMP9ALDH1A1 | |
| SCHEMBL2442905 | 0.77 | TRPA1 (0.43) | MMP1MMP3MMP7MMP9SMN1; SMN2 | |
| SCHEMBL2444913 | 0.77 | TRPA1 (0.43) | MMP1MMP3MMP7MMP9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009004-A1 | NOVEL PIPERAZINE COMPOUND, AND USE THEREOF AS HCV POLYMERASE INHIBITOR | Japan Tobacco, Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |