SCHEMBL4580221

SCHEMBL4580221

C=CC(=O)OCCOC(=O)c1cccc(C(=O)O)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.51
ALDH1A1 P00352 8/20 0.43
TSHR P16473 7/20 0.43
HSD17B10 Q99714 4/20 0.43
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HMGB1 P09429 1/20 0.42
CYP3A4 P08684 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
HPGD P15428 3/20 0.40
KDM4E B2RXH2 2/20 0.40
ALB P02768 1/20 0.40
MMP2 P08253 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
GLA P06280 1/20 0.39
MAPK1 P28482 1/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67527 0.86 THRB (0.59) THRBALDH1A1TSHRHSD17B10TP53
SCHEMBL30198617 0.86 THRB (0.59) THRBALDH1A1TSHRHSD17B10TP53
SCHEMBL19210181 0.85 THRB (0.51) THRBALDH1A1TSHRHSD17B10TP53
SCHEMBL228020 0.82 THRB (0.62) THRBALDH1A1TSHRHSD17B10TP53
Formic Acid SCHEMBL22720643 0.82 THRB (0.55) THRBALDH1A1TSHRHSD17B10TP53
SCHEMBL30408129 0.82 ALDH1A1 (0.51) THRBALDH1A1TSHRHSD17B10TP53
Phthalic Acid SCHEMBL31121837 0.81 TSHR (0.53) THRBALDH1A1TSHRHSD17B10TP53
SCHEMBL29625496 0.81 TSHR (0.53) THRBALDH1A1TSHRHSD17B10TP53
SCHEMBL1110903 0.81 TSHR (0.53) THRBALDH1A1TSHRHSD17B10TP53
SCHEMBL7115629 0.81 TSHR (0.55) THRBALDH1A1TSHRHSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-7220529-B2 Photopolymerizable composition and recording material using the same FUJIFILM CORPORATION (JP) 2007-05-22 US disclosed
US-20070048666-A1 Two-photon recording method, two-photon absorption recording material, two-photon absorption recording-reproduction method and optical recoding medium FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070047038-A1 Hologram recording method, hologram recording material, optical recording medium FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20050186504-A1 Photopolymerizable composition and recording material using the same FUJI PHOTO FILM CO., LTD. 2005-08-25 US disclosed
US-20050187102-A1 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-08-25 US disclosed
US-20050158548-A1 Microcapsule, manufacturing method thereof and recording material FUJI PHOTO FILM CO., LTD. 2005-07-21 US disclosed
US-6919159-B2 Photopolymerizable composition and recording material using the same FUJI PHOTO FILM CO., LTD. (JP) 2005-07-19 US disclosed
US-6846605-B2 Photopolymerizable composition and recording material using same FUJI PHOTO FILM CO., LTD. (JP) 2005-01-25 US disclosed
EP-1298490-A2 Photopolymerizable composition and recording material Fuji Photo Film Co., Ltd. (JP) 2003-04-02 EP disclosed
US-20020182530-A1 Polymerizable compound having an ethylenic unsaturated bond, a methine dye, and a radical generator that interacts with the dye to generate a radical FUJI PHOTO FILM CO., LTD. 2002-12-05 US disclosed
US-20020168494-A1 Photopolymerizable composition and photosensitive thermal recording material FUJI PHOTO FILM CO., LTD. 2002-11-14 US disclosed
US-20020142244-A1 Photopolymerizable composition and recording material FUJI PHOTO FILM CO., LTD. 2002-10-03 US disclosed
US-20020051926-A1 Cyanine-based organic dyes, photopolymerizable compositions, and recording materials FUJI PHOTO FILM CO., LTD. (JP) 2002-05-02 US disclosed
US-6022664-A MIXTURE OF A POLYMERIZABLE VINYL MONOMER AND ORGANIC BORATE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2000-02-08 US disclosed
EP-0412570-B1 Light- and heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 1996-07-10 EP disclosed
US-5376495-A Microcapsules from solution containing component capable of undergoing color development or achromatization and volatile solvent FUJI PHOTO FILM CO., LTD. (JP) 1994-12-27 US disclosed
US-5091280-A Photothermography; microencapsulated leuco dyes, polymerizable vinyl monomer, photoinitiator electron acceptive developer FUJI PHOTO FILM CO., LTD. (JP) 1992-02-25 US disclosed
EP-0412570-A2 Light- and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-02-13 EP disclosed