SCHEMBL4580407

SCHEMBL4580407

C=C(C#N)C(=O)OCCCCOC(=O)C(=C)C#N

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.63
ALDH1A1 P00352 2/20 0.63
DNM1 Q05193 3/20 0.38
CYP3A4 P08684 1/20 0.37
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.32
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1983908 0.98 TSHR (0.61) TSHRALDH1A1DNM1CYP3A4POLB
SCHEMBL4581824 0.98 TSHR (0.61) TSHRALDH1A1DNM1CYP3A4POLB
SCHEMBL11674143 0.98 TSHR (0.61) TSHRALDH1A1DNM1CYP3A4POLB
SCHEMBL1982870 0.98 TSHR (0.61) TSHRALDH1A1DNM1CYP3A4POLB
SCHEMBL11672299 0.98 TSHR (0.61) TSHRALDH1A1DNM1CYP3A4POLB
SCHEMBL1982599 0.98 TSHR (0.61) TSHRALDH1A1DNM1CYP3A4POLB
SCHEMBL4581421 0.98 TSHR (0.61) TSHRALDH1A1DNM1CYP3A4POLB
SCHEMBL4578754 0.95 TSHR (0.63) TSHRALDH1A1DNM1CYP3A4POLB
SCHEMBL27907823 0.92 TSHR (0.55) TSHRALDH1A1DNM1CYP3A4POLB
SCHEMBL4579700 0.91 TSHR (0.68) TSHRALDH1A1DNM1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4194523-A1 CYANOACRYLATE ADHESIVE COMPOSITION Cuantum Medical Cosmetics, S.L. (ES) 2023-06-14 EP claimed
WO-2021115318-A1 SUPERHYDROPHOBIC WATER-REPELLENT LIQUID, PREPARATION METHOD, AND APPLICATION THEREOF IN WATERPROOF SOUND-PERMEABLE MESH 佛山市思博睿科技有限公司 2021-06-17 WO claimed
CN-1239653-C Cyanoacrylate compositions, reaction products, methods of preparation and uses thereof LOCTITE R & D LTD (IE) 2006-02-01 CN claimed
CN-1487983-A Cyanoacrylate compositions curable to flexible polymeric materials ���̩��(R&D)���޹�˾ 2004-04-07 CN claimed
EP-4194523-A1 CYANOACRYLATE ADHESIVE COMPOSITION Cuantum Medical Cosmetics, S.L. (ES) 2023-06-14 EP disclosed
US-10833351-B2 Solid electrolyte composition, solid electrolyte-containing sheet, all-solid state secondary battery, and methods for manufacturing solid electrolyte composition, solid electrolyte-containing sheet, all-solid state secondary battery FUJIFILM CORPORATION (JP) 2020-11-10 US disclosed
CN-110903763-A Super-hydrophobic waterproof liquid, preparation method thereof and preparation method of waterproof sound-transmitting net thereof 佛山市思博睿科技有限公司 2020-03-24 CN disclosed
US-20190006700-A1 SOLID ELECTROLYTE COMPOSITION, SOLID ELECTROLYTE-CONTAINING SHEET, ALL-SOLID STATE SECONDARY BATTERY, AND METHODS FOR MANUFACTURING SOLID ELECTROLYTE COMPOSITION, SOLID ELECTROLYTE-CONTAINING SHEET, ALL-SOLID STATE SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2019-01-03 US disclosed
US-7341716-B2 Occlusive composition BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-03-11 US disclosed
EP-1494999-B1 OCCLUSIVE COMPOSITION COMPRISING A POLY(2-CYANOACRYLATE) MONOMER BOSTON SCIENT LTD (BB) 2006-06-07 EP disclosed
CN-1239653-C Cyanoacrylate compositions, reaction products, methods of preparation and uses thereof LOCTITE R & D LTD (IE) 2006-02-01 CN disclosed
EP-1494999-A1 OCCLUSIVE COMPOSITION COMPRISING A POLY(2-CYANOACRYLATE) MONOMER Boston Scientific Limited (BB) 2005-01-12 EP disclosed
US-20030194389-A1 Occlusive composition STRYKER CORPORATION 2003-10-16 US disclosed
US-4041062-A CROSSLINKING AGENTS FOR DENTAL ADHESIVE, SEALING OR COATING POLYMERS JOHNSON & JOHNSON (US) 1977-08-09 US disclosed
US-4041063-A CROSSLINKING AGENTS FOR DENTAL ADHESIVE, SEALING OR COATING POLYMERS JOHNSON & JOHNSON (US) 1977-08-09 US disclosed
US-4041061-A CROSSLINKING AGENTS FOR DENTAL ADHESIVE, SEALING OR COATING POLYMERS JOHNSON & JOHNSON (US) 1977-08-09 US disclosed
US-4013703-A CROSSLINKING AGENTS; MONOMERS FOR ADHESIVE POLYMERS JOHNSON & JOHNSON (US) 1977-03-22 US disclosed
US-4012402-A Modified cyanoacrylate monomers and methods for preparation JOHNSON & JOHNSON (US) 1977-03-15 US disclosed
US-4003942-A CROSSLINKING AGENTS; DENTAL ADHESIVES JOHNSON & JOHNSON (US) 1977-01-18 US disclosed
US-3975422-A Preparation of bis (2-cyanoacrylate)monomers JOHNSON & JOHNSON (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030194389-A1 Occlusive composition C3AR1, F12, FGB TSHR 3434/4885ALDH1A1 1135/4885DNM1 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.