SCHEMBL4580447

SCHEMBL4580447

CCN(CC)S(=O)(=O)c1cc(F)cc(F)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.53
HTT P42858 4/20 0.53
LMNA P02545 2/20 0.53
ALDH1A1 P00352 7/20 0.52
TSHR P16473 1/20 0.52
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
KDM4E B2RXH2 2/20 0.47
NPSR1 Q6W5P4 2/20 0.46
MAPT P10636 3/20 0.45
KDM1A O60341 1/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
MAPK1 P28482 1/20 0.44
SERPINE1 P05121 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3246445 0.79 ALDH1A1 (0.73) SMN1; SMN2HTTLMNAALDH1A1TSHR
SCHEMBL196165 0.75 HTT (0.53) SMN1; SMN2HTTLMNAALDH1A1TSHR
SCHEMBL197477 0.75 ALDH1A1 (0.54) SMN1; SMN2HTTLMNAALDH1A1TSHR
SCHEMBL196097 0.75 SMN1; SMN2 (0.53) SMN1; SMN2HTTLMNAALDH1A1TSHR
SCHEMBL27345155 0.75 HTT (0.67) SMN1; SMN2HTTLMNAALDH1A1TSHR
SCHEMBL30811628 0.75 HTT (0.67) SMN1; SMN2HTTLMNAALDH1A1TSHR
SCHEMBL13286822 0.73 SERPINE1 (0.58) SMN1; SMN2HTTLMNAALDH1A1TSHR
SCHEMBL778022 0.73 PSIP1 (0.46)
SCHEMBL31647093 0.72 ALDH1A1 (0.60) SMN1; SMN2HTTLMNAALDH1A1TSHR
SCHEMBL3017768 0.71 HTT (0.57) SMN1; SMN2HTTLMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080312349-A1 METHOD OF MAKING AND USING MEMBRANE GENERAL ELECTRIC COMPANY (US) 2008-12-18 US disclosed
WO-2008103599-A2 COMPOSITION, ITS USE IN THE PREPARATION OF MEMBRANES, AND SYSTEMS COMPRISING THE MEMBRANES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-28 WO disclosed
US-20080203012-A1 MEMBRANE, APPARATUS, AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed
US-20080207822-A1 COMPOSITION AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed