⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458050 | 1.00 | — | — | |
| SCHEMBL14388431 | 1.00 | — | — | |
| SCHEMBL866068 | 1.00 | — | — | |
| SCHEMBL8186028 | 1.00 | — | — | |
| SCHEMBL8186027 | 1.00 | — | — | |
| SCHEMBL13406449 | 1.00 | — | — | |
| SCHEMBL15703578 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL74585 | 0.98 | GRIK1 (0.66) | — | |
| Hydrochloric Acid SCHEMBL712566 | 0.98 | GRIK1 (0.66) | — | |
| Hydrochloric Acid SCHEMBL713389 | 0.98 | GRIK1 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4071477-B1 | COMPOSITIONS AND METHODS FOR DIAGNOSING LYME DISEASE AND FOR PREDICTING LYME DISEASE SPIROCHETE ELIMINATION AFTER TREATMENT | QIAGEN SCIENCES LLC (US) | 2026-01-21 | — | — | EP | disclosed |
| US-20240384267-A1 | COMPOSITIONS AND METHODS FOR MULTIPLEX DECODING OF QUADRUPLET CODONS | THE BROAD INSTITUTE, INC. | 2024-11-21 | — | — | US | disclosed |
| US-20240361314-A1 | COMPOSITIONS AND METHODS FOR DIAGNOSING LYME DISEASE AND FOR PREDICTING LYME DISEASE SPIROCHETE ELIMINATION AFTER TREATMENT | QIAGEN SCIENCES LLC (US) | 2024-10-31 | — | — | US | disclosed |
| US-20240294586-A1 | TENASCIN-C AUTOANTIGENIC EPITOPES IN RHEUMATOID ARTHRITIS | BENAROYA RES INSTITUTE AT VIRGINIA MASON (US) | 2024-09-05 | — | — | US | disclosed |
| US-12066436-B2 | Compositions and methods for diagnosing Lyme disease and for predicting Lyme disease spirochete elimination after treatment | QIAGEN SCIENCES LLC (US) | 2024-08-20 | — | — | US | disclosed |
| US-20240027450-A1 | COMPOSITIONS AND METHODS FOR DIAGNOSING SARS-COV-2 (COVID-19) AND FOR MONITORING SARS-COV-2-SPECIFIC IMMUNOLOGICAL MEMORY | QIAGEN SCIENCES LLC | 2024-01-25 | — | — | US | disclosed |
| EP-4256334-A1 | COMPOSITIONS AND METHODS FOR DIAGNOSING SARS-COV-2 (COVID-19) AND FOR MONITORING SARS-COV-2-SPECIFIC IMMUNOLOGICAL MEMORY | Qiagen Sciences LLC (US) | 2023-10-11 | — | — | EP | disclosed |
| WO-2023069816-A2 | COMPOSITIONS AND METHODS FOR MULTIPLEX DECODING OF QUADRUPLET CODONS | THE BROAD INSTITUTE, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| EP-3353551-B1 | COMPOSITIONS AND METHODS FOR DIAGNOSING LYME DISEASE AND FOR PREDICTING LYME DISEASE SPIROCHETE ELIMINATION AFTER TREATMENT | QIAGEN SCIENCES LLC (US) | 2022-11-02 | — | — | EP | disclosed |
| EP-4071477-A1 | COMPOSITIONS AND METHODS FOR DIAGNOSING LYME DISEASE AND FOR PREDICTING LYME DISEASE SPIROCHETE ELIMINATION AFTER TREATMENT | QIAGEN Sciences, LLC (US) | 2022-10-12 | — | — | EP | disclosed |
| US-20080026422-A1 | Adding an desired amino acid analog to a medium containing a host cell with a vector coding for aminoacyl-tRNA synthetase and a vector coding for the polypeptide of interest; and growing the cell to produce the modified polypeptide | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-01-31 | — | — | US | disclosed |
| WO-2008005531-A2 | C-MET RECEPTOR REGULATION BY ANGIOTENSIN IV (AT4) RECEPTOR LIGANDS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-01-10 | — | — | WO | disclosed |
| US-20080008701-A1 | C-MET RECEPTOR REGULATION BY ANGIOTENSIN IV (AT4) RECEPTOR LIGANDS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-01-10 | — | — | US | disclosed |
| WO-2007130453-A2 | NON-NATURAL AMINO ACID SUBSTITUTED POLYPEPTIDES | ALLOZYNE, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007103307-A2 | SITE-SPECIFIC INCORPORATION OF AMINO ACIDS INTO MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-09-13 | — | — | WO | disclosed |
| US-7198915-B2 | Preparing modified/artificial polypeptides; mimetics | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-04-03 | — | — | US | disclosed |
| US-7198915-B2 | Preparing modified/artificial polypeptides; mimetics | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-04-03 | — | — | US | disclosed |
| US-20040058415-A1 | Preparing modified/artificial polypeptides; mimetics | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-03-25 | — | — | US | disclosed |
| US-6586207-B2 | Host cell is a methionine auxotroph; methionine-tRNA synthetase overexpressed in presence of analogues and absence of methionine; protein is modified dihydrofolate reductase | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-07-01 | — | — | US | disclosed |
| US-20020042097-A1 | Host cell is a methionine auxotroph; methionine-tRNA synthetase overexpressed in presence of analogues and absence of methionine; protein is modified dihydrofolate reductase | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-04-11 | — | — | US | disclosed |